An extract from the culture of a thermophilic <i>Staphylococcus aureus</i> strain suppresses allergic inflammation in the airways <i>in vivo</i> and degranulation of mast cells and basophils <i>in vitro</i>
Abstract:Aim. To study the anti-allergic effects of ruzam, an extract from the culture of a thermophilic Staphylococcus aureus strain, in an in vivo model of asthma and its influence on degranulation of mast cells and basophils in vitro.Materials and methods. Allergic asthma in guinea pigs was reproduced by two intraperitoneal injections of ovalbumin followed by a series of inhalations of this antigen for 1.5 months. Ruzam (6 μg / kg) or a reference drug (sodium cromoglycate, 3 mg / kg) was administered daily via a neb… Show more
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