An Extensive Outbreak of Gastroenteritis Caused by Salmonella Newport

Bille, B; Mellbin, Tore; Nordbring, Folke

doi:10.1111/j.0954-6820.1964.tb00607.x

Cited by 24 publications

(1 citation statement)

References 22 publications

(15 reference statements)

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“…1e3 Persistent excretion following NTS infection has been well documented. 4,5 Numerous studies have suggested that Salmonella carriers can cause or perpetuate outbreaks of salmonellosis]. 6e9 Routine antimicrobial treatment of uncomplicated gastroenteritis caused by Salmonella species has been discouraged because it does not reduce the duration or severity of illness and may prolong asymptomatic carriage.…”

Section: Introductionmentioning

confidence: 99%

Factors affecting fecal excretion time in pediatric nontyphoid Salmonella infection

Chen

Cheng

et al. 2021

Pediatrics & Neonatology

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Background: This study investigated whether the appropriate antibiotics therapy affects the fecal excretion time in pediatric salmonellosis of different severities and explored the factors associated with the fecal excretion time of nontyphoid Salmonella. Methods: Between 2012 and 2017, admitted children with nontyphoid salmonellosis who consented to receive consecutive stool cultures every 4e7 days until 2 consecutive negative results were obtained were enrolled. Patients were stratified into no, appropriate (bacteremia or severe patients receiving antibiotics active in vitro), and inappropriate antibiotics (patients with mild or moderate severity receiving antibiotics or severe receiving antibiotics resistant in vitro) therapy groups. A previously proposed severity score was used to classify the patients into severe, moderate, and mild severity classes. The demographics, clinical manifestations, laboratory data and severity were compared among the groups. To explore the factors associated with the fecal excretion time of nontyphoid Salmonella, univariate and multivariate analyses were performed using linear regression analysis. Results: This study enrolled 126 children with nontyphoid salmonellosis; 58 and 18 in the mild and severe classes, respectively. The no, appropriate and inappropriate antibiotics therapy groups comprised 69, 24 and 33 patients, respectively. The mean fecal excretion time was 12.17 days. The appropriate antibiotics therapy group had comparable fecal excretion time with that of no antibiotics group. Age <1 year, increased white blood cell count, decreased hemoglobin, and inappropriate antibiotics therapy significantly prolonged fecal excretion time in univariate analysis (p < 0.05). The multivariate analysis showed that inappropriate * Corresponding author. No.386, Dazhong 1st Rd.

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Section: Introductionmentioning

confidence: 99%

Factors affecting fecal excretion time in pediatric nontyphoid Salmonella infection

Chen

Cheng

et al. 2021

Pediatrics & Neonatology

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The Influence of Immunity on Raw Milk— Associated Campylobacter Infection

Blaser

Sazie²,

Williams

1987

JAMA

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After a retreat to an Oregon farm, 19 of 31 college students developed an acute gastrointestinal illness. Campylobacter jejuni infection was recognized in all the ill students and caused asymptomatic infections in three others. In total, 22 (88%) of 25 students who consumed raw milk for the first time became infected as compared with none of two who had not consumed raw milk. Among ten persons who chronically consumed raw milk, none was ill, a striking difference from the 76% attack rate among the 25 acutely exposed students. The quantity of raw milk consumed was directly related to the occurrence and severity of illness. Acutely infected students showed significant rises in C jejuni-specific immunoglobulins, whereas the low antibody levels seen in unexposed persons did not rise. In contrast, acute-phase serum samples from persons with chronic exposure to raw milk showed elevated antibody levels to C jejuni. These findings indicate that chronic raw milk consumption is associated with elevated levels of C jejuni-specific serum antibodies and with immunity to symptomatic infection.

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Salmonellosis: Nontyphoidal

Snydman

Gorbach

1982

Bacterial Infections of Humans

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An Extensive Outbreak of Gastroenteritis Caused by Salmonella Newport

Cited by 24 publications

References 22 publications

Factors affecting fecal excretion time in pediatric nontyphoid Salmonella infection

Factors affecting fecal excretion time in pediatric nontyphoid Salmonella infection

The Influence of Immunity on Raw Milk— Associated Campylobacter Infection

Salmonellosis: Nontyphoidal

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