An Extension of DNA Splicing System

In DNA splicing system, the potential effect of sets of restriction enzymes and a ligase that allow DNA molecules to be cleaved and re-associated to produce further molecules is modelled mathematically. This modelling is done in the framework of formal language theory, in which the nitrogen bases, nucleotides and restriction sites are modelled as alphabets, strings and rules respectively. The molecules resulting from a splicing system is depicted as the splicing language. In this research, the splicing language resulting from DNA splicing systems with one palindromic restriction enzyme for one and two (non-overlapping) cutting sites are generalised as regular expressions.

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“…for the first cutting site and 11) for the second cutting site. The initial string can be written 180 degree wise as…”

Section: Resultsmentioning

confidence: 99%

“…A splicing language is a language resulting from a splicing system. There are many types of splicing languages such as persistent, strictly locally testable and uniform splicing language which have been discussed in [2,11,12]. Besides, simple spicing languages are defined by Laun [8] in 1999.…”

Section: Introductionmentioning

confidence: 99%

Generalisations of DNA Splicing Systems with One Palindromic Restriction Enzyme

Fong

Ismail

2018

MATEMATIKA

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“…The motivation of this study is the new formalism of splicing system proposed by Yusof and Goode in 2012, where Yusof [8] introduced the new writing notation called Yusof-Goode (Y-G) splicing system with the objective of investigating the behavior of restriction enzyme acting on DNA molecule in a translucent approach.…”

Section: Dna Splicing System and Its Historymentioning

confidence: 99%

A Bibliometric Review on Deoxyribonucleic Acid (DNA) Splicing System

Nooradelena Mohd Ruslim,

Yuhani Yusof,

Mohd Sham Mohamad

et al. 2024

ARMNE

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This study objects to provide a communicative review for splicing system, focusing on deoxyribonucleic acid (DNA) published in journals and proceedings indexed by the Scopus database. The method of bibliometric analysis is used to describe and analyze the evolution of publication structure and its various co-relationships such as citation, co-citation, co-authorship, and co-occurrence, among the chosen 174 documents indexed by Scopus. This study gives some insightful direction of research where the most influential documents and authors were determined. Besides, the emerging of technologies in most of the research works conducted previously promote the hybridization of background of studies specifically in mathematics, biology, and computer science. The study is limited to English articles which was published by the Scopus database, ranging from the year of 1983 until 2023. The source is also limited to Scopus journals and proceedings only. As far as the authors are aware, this is the first study to address the splicing system topic from a bibliometric perspective. The authors believe that this bibliometric review will help scholars and researchers to stand firm bases regarding the scientific development of this field of study.

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“…Besides, splicing systems are a class of formal language systems originally introduced in the context of molecular biology perspectives involving cutting and pasting the DNA molecule in the presence of restriction enzymes and ligase. The splicing system includes Head [3], Paun [5], Pixton [6], Goode-Pixton [7], Yusof-Goode [8] and fuzzy splicing systems [9].…”

Section: Introductionmentioning

confidence: 99%

Classification of n-th Order Limit Language in Formal Language Classes

Siti Hajar Mohd Khairuddin,

Muhammad Azrin Ahmad,

Mohd Sham Mohamad

2024

ARASET

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The study of splicing systems and their language has grown rapidly since Paun developed a splicing system known as a regular splicing scheme that produces a regular language. Since then, the researchers have been eager to classify the splicing language into certain classes in the Chomsky hierarchy, such as context-free language, context-sensitive language and recursive enumerable language. Previously, the study on the n-th order limit language was conducted from the biological perspective to the limit language produced. Still, no research has been done from the generation of language point of view. This research presents a generalization on the type of classes of the formal language, the n-th order limit language. The cases to obtain the n-th order limit language are revisited and used to obtain the types of language classes according to the Chomsky hierarchy produced by the n-th order limit language.

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An Extension of DNA Splicing System

Cited by 9 publications

References 6 publications

Generalisations of DNA Splicing Systems with One Palindromic Restriction Enzyme

Generalisations of DNA Splicing Systems with One Palindromic Restriction Enzyme

A Bibliometric Review on Deoxyribonucleic Acid (DNA) Splicing System

Classification of n-th Order Limit Language in Formal Language Classes

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