An Explanation of Signal Changes in DW-fMRI: Monte Carlo Simulation Study of Restricted Diffusion of Water Molecules Using 3D and Two-Compartment Cortical Cell Models
Abstract:SUMMARYDiffusion-weighted (DW)-functional magnetic resonance imaging (fMRI) is a recently reported technique for measuring neural activities by using diffusion-weighted imaging (DWI). DW-fMRI is based on the property that cortical cells swell when the brain is activated. This approach can be used to observe changes in water diffusion around cortical cells. The spatial and temporal resolutions of DW-fMRI are superior to those of blood-oxygenation-level-dependent (BOLD)-fMRI. To investigate how the DWI signal in… Show more
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