An expert survey for developing pattern diagnosis instrument of persistent allergic rhinitis

Kim

et al. 2021

Preprint

Background and objectives: While pattern identification (PI) is an essential process for diagnosis and treatment in traditional Asian medicine (TAM), it is difficult to objectify since it relies heavily on implicit knowledge. Here, we propose a machine learning-based analysis tool to objectify and evaluate the clinical decision-making process of PI in terms of explicit and implicit knowledge. Methods: Clinical data for the development of the analysis tool were collected using a questionnaire administered to allergic rhinitis (AR) patients and the diagnosis and prescription results of TAM doctors based on the completed AR questionnaires. Explicit knowledge and implicit knowledge were defined based on the explicit and implicit importance scores of the AR questionnaire, which were obtained through doctors′ explicit scoring and feature evaluations of machine learning models, respectively. The analysis tool consists of eight evaluation indicators used to compare, analyze and visualize the explicit and implicit knowledge of TAM doctors. Results: The analysis results for 8 doctors showed that our tool could successfully identify explicit and implicit knowledge in the PI process. We also conducted a postquestionnaire study with the doctors who participated to evaluate the applicability of our tool. Conclusions: This study proposed a tool to evaluate and compare decision-making processes of TAM doctors in terms of their explicit and implicit knowledge. We identified the differences between doctors′ own explicit and implicit knowledge and the differences among TAM doctors. The proposed tool would be helpful for the clinical standardization of TAM, doctors′ own clinical practice, and intern/resident training.

“…The gender ratio in each group was 1:1. We used the PI questionnaire developed from previous studies (Supplementary Table 1) [14][15][16][17][18].…”

Section: Participants Sample Size and The Questionnaire (Step 1)mentioning

confidence: 99%

Development of an explicit and implicit knowledge identification tool for the analysis of the decision-making process of traditional Asian medicine doctors

Kim

et al. 2021

Preprint

“…20 However, that questionnaire had many problems in application to clinical practice and has since been revised based on several studies and discussions. [21][22][23] Consequently, the PI questionnaire for AR V.3.0 has been developed. 24 This questionnaire classifies patients with AR as possessing lung-heat, lung-cold or spleen qi deficiency and can be applied for both SAR and PAR.…”

Section: Pattern Identification By the Clinicianmentioning

confidence: 99%

Efficacy and safety of So-Cheong-Ryong-Tang in treatment of perennial allergic rhinitis: study protocol for a double-blind, randomised, parallel-group, multicentre trial

Kim

Ahn

et al. 2017

BMJ Open

Self Cite

IntroductionSo-Cheong-Ryong-Tang (SCRT) is a herbal medicine widely used in traditional medicine for treating allergic rhinitis (AR). In animal studies, SCRT has suppressed the progression of AR. The main purpose of this study is to assess the efficacy and safety of the SCRT for the treatment of perennial allergic rhinitis (PAR) and discover the underlying mechanisms resulting in anti-inflammatory effects in humans.Methods and analysisWe will conduct a double-blind, randomised, placebo-controlled, parallel-group, multicentre trial of Korean adults with PAR. For the study, 156 subjects with PAR will be recruited. The trial will consist of a 4-week oral administration of SCRT or placebo with two visits at 2-week intervals and an 8-week follow-up period with two visits at 4-week intervals. The primary outcome is a change in the total nasal symptoms score. The secondary outcomes include changes in the Rhinoconjunctivitis Quality of Life Questionnaire score, total serum IgE and cytokines levels.Ethics and disseminationThis study was approved by the Institutional Review Board at each research centre (name of each centres and approval numbers): Kyung Hee University Hospital at Gangdong (KHNMC-OH-IRB 2015-04-009), Kyung Hee University Medical Centre (KOMCIRB-160321-HRBR-011), Pusan National University Hospital (2016–004), Dongguk University Medical Centre (2016–03) and Semyung University hospital (2016–01). This result will be published in a peer-reviewed journal.Trial registration numberNCT03009136; Pre-results.

Journal of Oriental Neuropsychiatry

“…한의학계에 서도 이러한 문제점을 인지하고 변증의 한계를 극복하기 위 한 다양한 연구들을 시행하였다. 특히 알레르기 비염 13) , 기 능성 소화불량 14) , 폐암 15) , 위-식도 역류질환 16) , 만성 기침 17) 등 다양한 질환에 대한 변증 도구 개발 시도가 있었으며, 신경정신과 영역에서도 화병(火病) 18,19) , 경계정충(驚悸怔忡) 20 …”

Section: 한의학에서는 망(望) 문(聞) 문(問) 절(切)의 사진(四診)unclassified

Preliminary Study to Develop the Instrument on Pattern Identifications for Insomnia

Lee¹,

Kim²,

Yun³

et al. 2016

Objectives: This study was carried out to develop a standard tool of pattern identifications for insomnia in Korean Medicine. Methods: The advisory committee for this study was organized by 17 Korean Medicine neuropsychiatry professors who were faculty members of different Korean Medicine colleges. The pattern identifications and symptoms for this tool were extracted from published Korean and Chinese literature. The Instrument on Pattern Identifications for Insomnia was developed following discussions among internal experts and after consultations with members of the advisory committee. Results: 1) Five pattern identifications were set for the tool. 2) The mean weights which represent the importance of each symptom and scored on a hundred-point scale were obtained. 3) The Instrument on Pattern Identifications for insomnia was designed in the self-reporting format composed of 47 questions. Conclusions: An Instrument on Pattern Identifications for Insomnia was created in this study. However, owing to any clinical trials has not been set yet. Therefore its validity and reliability were not confirmed. To make up for this limitation, the further clinical study would be performed in the near future.