Unreinforced masonry (URM) buildings are highly vulnerable to seismic ground motion, calling for quantitative risk assessment and mitigation programmes in different earthquakeâprone countries to reduce future losses. Despite the effectiveness of base isolation technology in reducing seismic response of buildings, the high costs of conventional isolators prevent their application to lowâcost housing in developing countries. Fiberâreinforced elastomeric isolators (FREIs) have been recently developed as lowâcost isolators suitable for application to URM buildings. The structural performance assessment of base isolated URM buildings using FREIs can be a sustainable solution for a largeâscale mitigation of seismic risk. In this context, the present study presents the seismic fragility analysis of both fixedâbase and baseâisolated URM buildings. Five URM building archetypes were considered to account for variation in geometry and building configuration. A number of static pushover analyses and nonlinear time history analyses were carried out to assess the capacity and demand of the selected buildings, respectively, while considering the uncertainties associated with material properties, capacity model, damage state and earthquake ground motion. The fragility curves were developed for both fixedâbase and baseâisolated configurations of the different archetypes. The results show that the probability of slight to moderate damage to fixedâbase URM buildings is significantly higher than their baseâisolated counterparts, demonstrating that FREIs significantly improve their seismic performance. These outcomes address further research in promoting the development of FREIs to reduce the vulnerability of URM buildings in developing countries.