An Experimental Study of the Possibility of Transmitting Syphilis by a Corneal Graft*

Randolph, M. Elliott

doi:10.1016/0002-9394(52)90006-8

Cited by 10 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Failure of corneas to transmit the syphilis spirochete has been demonstrated in animal experiments in which corneas were transplanted from rabbits with latent or active syphilis (Randolph 1952). Corneas would be unlikely to transmit syphilis to humans since, among other reasons, corneas are usually stored at low temperatures and these temperatures reduce spirochete viability and infectivity.…”

Section: Bacterial Infection From Transplantation Of Corneal Allograftsmentioning

confidence: 99%

Bacterial infection transmitted by human tissue allograft transplantation

Eastlund

2006

Cell Tissue Banking

123

View full text Add to dashboard Cite

Bacterial contamination of tissue allografts obtained from cadaveric donors has been a serious cause of morbidity and mortality in recipients. Recent cases of fatal and nonfatal bacterial infections in recipients of contaminated articular cartilage (distal femur) and tendon allografts have called attention to the importance of avoiding tissue donors suspected of carrying infectious disease, of not processing donated tissue carrying virulent bacteria, the occurrence of falsely negative final sterility tests, and the need to sterilize tissues. These cases demonstrated that contamination can arise from an infected donor, during tissue removal from cadaveric donors, from the processing environment, and from contaminated supplies and reagents used during processing. Final sterility testing can be unreliable, especially when antibiotics remain on tissues. There is an increasing need for control of microbial contamination in tissue banks, and sterilization of tissue allografts should be recommended whenever possible.

show abstract

Section: Bacterial Infection From Transplantation Of Corneal Allograftsmentioning

confidence: 99%

Bacterial infection transmitted by human tissue allograft transplantation

Eastlund

2006

Cell Tissue Banking

123

View full text Add to dashboard Cite

show abstract

“…One study demonstrated an inability to infect healthy rabbits (both systemically and ocularly) with syphilis bacteria T. pallidum despite ocular and systemic inoculations of a syphilisinfected corneal concoction. 36 In addition, T. pallidum loses infectivity potency when corneas are stored in standard storage materials. 37 There have been no documented cases of transmitted syphilis from ocular tissue to date.…”

Section: Syphilismentioning

confidence: 99%

The structure and evolution of eye banking: a review on eye banks’ historical, present, and future contribution to corneal transplantation

Lambert¹,

Chamberlain²

2017

BSAM

View full text Add to dashboard Cite

The purpose of this review is to describe the increasing roles and responsibilities of eye banking with focus on its roles in the US historically, currently, and in the future. Since the establishment of the first eye bank by Townley Paton in 1944, eye banks have been responsible for both the safety and quality of corneal graft procurement, preparation, and distribution. Over time, eye banks have played an increasing role in the evolving world of corneal transplantation. Eye banks have repeatedly risen to new challenges regarding disease transmission, preparation of partial-thickness graft preparation, use of novel technology, and adjustment to meet constant increasing legislation and regulation. As the future will likely bring new opportunities as well as challenges, eye banks need to continually adapt to future technical and regulatory obstacles, ensuring that the future of corneal transplantation continues to be increasingly safe and successful.

show abstract

Cornea and Sclera

Berliner¹

1951

AMA Arch Ophthalmol

View full text Add to dashboard Cite

An Experimental Study of the Possibility of Transmitting Syphilis by a Corneal Graft*

Cited by 10 publications

References 10 publications

Bacterial infection transmitted by human tissue allograft transplantation

Bacterial infection transmitted by human tissue allograft transplantation

The structure and evolution of eye banking: a review on eye banks’ historical, present, and future contribution to corneal transplantation

Cornea and Sclera

Contact Info

Product

Resources

About

An Experimental Study of the Possibility of Transmitting Syphilis by a Corneal Graft*

Cited by 10 publications

References 10 publications

Bacterial infection transmitted by human tissue allograft transplantation

Bacterial infection transmitted by human tissue allograft transplantation

The structure and evolution of eye banking: a review on eye banks&rsquo; historical, present, and future contribution to corneal transplantation

Cornea and Sclera

Contact Info

Product

Resources

About

The structure and evolution of eye banking: a review on eye banks’ historical, present, and future contribution to corneal transplantation