An experimental study of the treatment of liver injury with InLine RFA

Abstract

InLine RFA is efficacious in treating liver injuries in pigs and may have a significant potential for some human liver injuries.

Novel Surgical Management of Renal Trauma: Inline Radiofrequency Ablation Coagulation

“…In our previous liver injury experiment, we have shown that ILRFA can achieve haemostasis in the liver trauma setting. Using ILRFA we were able to stop bleeding within 8 min with a 64% reduction of blood loss compared with controls in a simulated sharp injury animal model 9 . In our recently finished clinical study in liver resection, we showed that the median operation blood loss was 74.8% less in the ILRFA and postoperative complications were not increased compared with the control 22 …”

“…We have already shown that the bipolar InLine radiofrequency ablation device (ILRFA) significantly reduces blood loss in liver resection both in animal and clinical experiences 8 . In our previous liver trauma experiment, using ILRFA we successfully stopped bleeding within 8 min with a 64% reduction of blood loss compared with the control, a simulated sharp injury animal model 9 . In this study, we tested the ILRFA in the simulated renal injury where the injury is actively bleeding before an attempt at surgical control.…”

A multicentre controlled study of the InLine radiofrequency ablation device for liver transection

“…The ILRFA device has shown promising results in liver surgery. We have shown that it can achieve haemostasis in the liver trauma setting 28 . Using ILRFA we were able to stop bleeding within 8 min with a 63.88% reduction of blood loss in a simulated sharp injury animal model.…”

Radiofrequency-Assisted Hemostasis in a Trauma Model: A New Indication for a Bipolar Device

“…[15][16][17] Later, the application of RF energy was further extended to solid organ surgery, such as hepatectomy and partial splenectomy, using the same instruments. 5,18 Since then, few experimental [19][20][21][22] and clinical studies 23 were published describing the use of modified monopolar electrodes. Although RF solid organ surgery is related to minimal blood loss, it is not widely accepted because of the risk of septic complications.…”