The theoretical prediction of radioactive aerosol diffusion based on the instantaneous point source model is investigated, considering the effects of emission heights, ground reflection, dry deposition, wet deposition, radioactive decay and other factors based on the Gaussian diffusion model. Numerical simulations are performed to calculate the concentration distribution of the radioactive aerosol and to determine the evacuation zone. Simulation results show that the atmospheric stability tends to be the key factor of the radioactive aerosol distribution.