2006
DOI: 10.1205/cherd.05054
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An Experimental Investigation into the Scale-up of Oscillatory Flow Mixing in Baffled Tubes

Abstract: his paper describes results from an experimental investigation into the scale-up of oscillatory flow mixing (OFM) in geometrically scaled baffled tubes ranging from 24 mm to 150 mm diameter and from 1 m to 4.5 m in length. Measured axial dispersion coefficients are reported together with case studies and an empirical correlation. An alternative multi-orifice reactor geometry with the potential for use in large-scale plant was also constructed and tested from which it was concluded that OFM is a technology whic… Show more

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Cited by 66 publications
(88 citation statements)
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“…Generates increased particle flotation [33,34] increased mass transfer uniform bubble size and increased gas hold up produce enhanced mass transfer rates sixfold and 75% increases for oxygen transfer (k L a) into water and yeast culture, respectively [28,35] compact reactor design the ability to generate long residence times, under plug flow, with reduced reactor lengths allows compact designs up to a 600-fold decrease in reactor length compared with conventional tubular reactors [36] linear scale-up maintaining St, Re o and Re n allows mixing intensity and flow conditions to be predicted in large volume OBRs using data from laboratory-scale experiments laboratory-scale experiments can be scaled up by increasing OBR diameter or length while maintaining predictability [29,37,38] rsfs.royalsocietypublishing.org Interface Focus 3: 20120036…”
Section: Reduced Shear Ratementioning
confidence: 99%
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“…Generates increased particle flotation [33,34] increased mass transfer uniform bubble size and increased gas hold up produce enhanced mass transfer rates sixfold and 75% increases for oxygen transfer (k L a) into water and yeast culture, respectively [28,35] compact reactor design the ability to generate long residence times, under plug flow, with reduced reactor lengths allows compact designs up to a 600-fold decrease in reactor length compared with conventional tubular reactors [36] linear scale-up maintaining St, Re o and Re n allows mixing intensity and flow conditions to be predicted in large volume OBRs using data from laboratory-scale experiments laboratory-scale experiments can be scaled up by increasing OBR diameter or length while maintaining predictability [29,37,38] rsfs.royalsocietypublishing.org Interface Focus 3: 20120036…”
Section: Reduced Shear Ratementioning
confidence: 99%
“…St, Re o and Re n are assumed to fully define the fluid dynamic conditions for a particular OBR geometry [37]. By keeping these parameters constant, an OBR with a diameter of, for example, 24 mm should behave the same as one with a diameter of 150 mm.…”
Section: Direct Diameter Increasesmentioning
confidence: 99%
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“…An additional feature perhaps unique to OBCs is its linear scale-up in some particular applications, 15,[21][22][23] however no rules have yet been established in respect to scale-up of gas-liquid mixing in OBCs.…”
Section: Introductionmentioning
confidence: 99%