An excited state intramolecular proton transfer induced phosphate ion targeted ratiometric fluorescent switch to monitor phosphate ions in human peripheral blood mononuclear cells

Abstract

Detection of biological phosphate is very important for environmental and health care applications.

Tuning ESIPT-coupled luminescence by expanding π-conjugation of a proton acceptor moiety in ESIPT-capable zinc(ii) complexes with 1-hydroxy-1H-imidazole-based ligands

“…In this context, the application of ESIPT-fluorophores for a plethora of sensing purposes has become one of the mainstream interdisciplinary directions fusing together analytical, organic and physical chemistry. [56][57][58][59][60][61][62][63][64][65][66][67][68] Although the molecules of ESIPT-fluorophores can bind metal ions (which is used for the detection of metals), this phenomenon is typically coupled with their deprotonation and the disappearance of ESIPT in the metal complex molecules (Scheme 2, top). [69][70][71][72][73][74][75][76] Nevertheless, the purposeful design of specific sites for metal coordination in the molecules of ESIPT-fluorophores paves the way toward metal ion binding without the deprotonation of ESIPT-fluorophores (Scheme 2, bottom).…”

“…In this context, the application of ESIPT-fluorophores for a plethora of sensing purposes has become one of the mainstream interdisciplinary directions fusing together analytical, organic and physical chemistry. 56–68…”

A new ratiometric switch “two-way” detects hydrazine and hypochlorite via a “dye-release” mechanism with a PBMC bioimaging study

“…Thus, in continuation of our previous work, [51][52][53][54][55] we have introduced a new switch (HQCN), which can detect the toxic N 2 H 4 and OCl À in the presence of other guest analytes with two different outputs. The synthesis, photophysical characteristics, and applications of this probe are manifested by highlighting several essential features in detail in the following 'Results and discussion' section, which consists of eleven subsections.…”

First 1-hydroxy-1H-imidazole-based ESIPT emitter with an O–H⋯O intramolecular hydrogen bond: ESIPT-triggered TICT and speciation in solution

“…70–76 The sensitivity of ESIPT-capable molecules to abovementioned stimuli makes them promising sensors for analytical chemistry. 77–101…”