An evaluation of two techniques for beam intensity modulation in patients irradiated for stage III non-small cell lung cancer

Koste, John van Sörnsen de; Voet, P.; Dirkx, M.; Meerbeeck, Jan Van; Senan, Suresh

doi:10.1016/s0169-5002(00)00214-2

Cited by 25 publications

(2 citation statements)

References 36 publications

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“…In addition, the post-chemotherapy GTV, both lungs, the spinal cord, the oesophagus and the heart were contoured on this second scan as described previously [18]. The GTV included the primary tumour volume and any mediastinal node with a short-axis diameter exceeding 1 cm.…”

Section: Methodsmentioning

confidence: 99%

A treatment planning study evaluating a ‘simultaneous integrated boost’ technique for accelerated radiotherapy of stage III non-small cell lung cancer

Dirkx

Koste²,

Senan³

2004

Lung Cancer

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Section: Methodsmentioning

confidence: 99%

A treatment planning study evaluating a ‘simultaneous integrated boost’ technique for accelerated radiotherapy of stage III non-small cell lung cancer

Dirkx

Koste²,

Senan³

2004

Lung Cancer

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“…33 IMRT has also been combined with stereotactic localization for delivering radiosurgery treatments to intracranial and extracranial sites using linear accelerators. 9, 34,35 Other sites of application include lung, [36][37][38] gastrointestinal tumors, [38][39][40][41] pediatric tumors, [42][43][44] and soft tissue sarcoma. 45 These data indicate that for certain clinical cases, there is a direct translation between dosimetric advantage and improved clinical outcome.…”

Section: Overviewmentioning

confidence: 99%

Planning and delivery of intensity‐modulated radiation therapy

Amies²,

Svatos

2008

Medical Physics

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Intensity modulated radiation therapy (IMRT) is an advanced form of external beam radiation therapy. IMRT offers an additional dimension of freedom as compared with field shaping in three-dimensional conformal radiation therapy because the radiation intensities within a radiation field can be varied according to the preferences of locations within a given beam direction from which the radiation is directed to the tumor. This added freedom allows the treatment planning system to better shape the radiation doses to conform to the target volume while sparing surrounding normal structures. The resulting dosimetric advantage has shown to translate into clinical advantages of improving local and regional tumor control. It also offers a valuable mechanism for dose escalation to tumors while simultaneously reducing radiation toxicities to the surrounding normal tissue and sensitive structures. In less than a decade, IMRT has become common practice in radiation oncology. Looking forward, the authors wonder if IMRT has matured to such a point that the room for further improvement has diminished and so it is pertinent to ask what the future will hold for IMRT. This article attempts to look from the perspective of the current state of the technology to predict the immediate trends and the future directions. This article will (1) review the clinical experience of IMRT; (2) review what we learned in IMRT planning; (3) review different treatment delivery techniques; and finally, (4) predict the areas of advancements in the years to come.

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A survey of intensity‐modulated radiation therapy use in the United States

Mell

Roeske

Mundt

2003

Cancer

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The interfacial area of mass transfer is one of the key parameters in valve tray design, and the valve geometry is the important structural parameter that determines the interfacial area. In this work, the hydrodynamic and mass‐transfer characteristics of three different types of valve trays are investigated. The mechanism of bubbles deformation and breakage in the turbulent dispersion system is theoretically analyzed on the basis of Kolmogoroff's isotropic turbulence hypothesis, and a novel model is proposed to predict the interfacial area. The results show that the simulation results agree well with the experimental data. In contrast to most of the conventional models, the present model is capable of evaluating the effects of valve configuration on the interfacial area. The model is expected to guide effectively the design of valve trays which is widely applied nowadays. © 2008 American Institute of Chemical Engineers AIChE J 2008

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An evaluation of two techniques for beam intensity modulation in patients irradiated for stage III non-small cell lung cancer

Cited by 25 publications

References 36 publications

A treatment planning study evaluating a ‘simultaneous integrated boost’ technique for accelerated radiotherapy of stage III non-small cell lung cancer

A treatment planning study evaluating a ‘simultaneous integrated boost’ technique for accelerated radiotherapy of stage III non-small cell lung cancer

Planning and delivery of intensity‐modulated radiation therapy

A survey of intensity‐modulated radiation therapy use in the United States

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