An evaluation of pulmonary atelectasis and its re-expansion

Evaluation of pulmonary reexpansion in a porcine model of bronchial foreign body

“…With these models, changes in pulmonary blood flow in both endobronchial obstruction for 24 h and subsequent repatency at 30, 60, and 90 min were analyzed. Similarly, Ferrante et al made Yorkshire pig's right main stem bronchus plugging through a Fogarty‐catheter occlusion balloon inflation, and described atelectasis and its reexpansion using MRI in a few minutes. Harada et al established a dog model of pulmonary reexpansion after atelectasis by two thoracotomes and found that the pulmonary function of dogs within 1 month of atelectasis was restored to normal levels.…”

“…A variety of animal models of bronchial FB obstruction have been established, however, given that positioning or removal of FBs is challenging, the long‐term process of pulmonary reexpansion still needs to be revealed. An occlusion balloon implantation method was used by Ricciardelli et al and Ferrante et al to establish an animal model of endobronchial obstruction and repatency. This model was used to analyze the changes in pulmonary blood flow and characteristics of magnetic resonance imaging (MRI) over a short period of time.…”

Pre-Syncope and Ataxia After Spinning Whiplash

“…It was published as a Rapid Communication in Neurosurgery [1]. She continued academic medicine pursuits in the subjects including the Surgical ICU [2][3][4][5], pulmonary hypertension [6], nitric oxide [7,8], ventilation/perfusion mismatch [9,10], and Hyperpolarized 3 He-MRI of the porcine lung [11][12][13]. She also presented multiple Poster Presentations and was a leader in her field, Hyperpolarized He-MRI of the lungs [14,15].…”

“…She also presented multiple Poster Presentations and was a leader in her field, Hyperpolarized He-MRI of the lungs [14,15]. She collaborated with other anesthesiologists, radiologists, internal medicine physicians, and physicists on projects [11][12][13] and helped write $3 million in successful NIH Research Grants at the University of Pennsylvania.…”

Ventilation Imaging Using Computed Tomography

“…Hounsfield units or HU) are linearly related in the range of water and dense bone and, important to the quantitative assessment of function, are proportional to the amount of contrast agent delivered to a lung region. While there are new methods emerging to image regional ventilation and perfusion via use of hyperpolarized gas in conjunction with MRI (1–9), the ability to image detailed anatomy of the lung along with the well characterized nature of reconstructed attenuation values in CT serves to place CT as the current gold standard for the assessment of lung structure and function. CT is easily available in every hospital and very cost‐competitive compared with (sometimes more invasive) other techniques.…”