2013
DOI: 10.1158/1940-6207.capr-13-0091
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An Evaluation of Novel, Lower-Cost Molecular Screening Tests for Human Papillomavirus in Rural China

Abstract: New, lower-cost tests that target high-risk human papillomavirus (HR-HPV) have been developed for cervical cancer screening in lower-resource settings but large, population-based screening studies are lacking. Women ages 25 to 65 years and living in rural China (n ¼ 7,543) self-collected a cervicovaginal specimen, had 2 cervical specimens collected by a clinician, and underwent visual inspection after acetic acid (VIA). The self-and one clinician-collected specimens underwent HR-HPV DNA testing by careHPV (QIA… Show more

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Cited by 89 publications
(104 citation statements)
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References 48 publications
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“…21,22,35 The findings of the current study endorse this premise because the careHPV test recognized high-grade intraepithelial lesions (CIN31). The performance indices confirm the hypothesis, with remarkably high sensitivity and negative predictive values obtained for the results of the HPV test, either alone or in association with cytology and visual inspection.…”
Section: Discussionsupporting
confidence: 67%
See 1 more Smart Citation
“…21,22,35 The findings of the current study endorse this premise because the careHPV test recognized high-grade intraepithelial lesions (CIN31). The performance indices confirm the hypothesis, with remarkably high sensitivity and negative predictive values obtained for the results of the HPV test, either alone or in association with cytology and visual inspection.…”
Section: Discussionsupporting
confidence: 67%
“…19,[21][22][23][24] Populations in many Brazilian regions have difficulty accessing public health assistance because many individuals reside in areas that are a distance from medical care facilities, roads (when they exist) are extremely bad, and public transportation is lacking. These conditions represent some of the principle motivations for the Barretos Cancer Hospital (BCH) to introduce the use of mobile units (MUs) in 1994 to attend to populations living in remote rural areas, including the midwest, southwest, and northern (Amazon) regions of Brazil; women in these regions comprise a significant percentage of the Brazilian population with HPV-induced lesions.…”
Section: Introductionmentioning
confidence: 99%
“…Elizabeth Barrios, MSc, (1) Patti Gravitt, PhD, (8) Anna Barbara Moscicki, MD, (9) Kathleen M Schmeler, MD, (10) Yvonne N Flores, PhD, (5,11) Pablo Méndez-Hernández, DSc, (11,12,13) Jorge Salmerón, DSc, (1,5) Torres-Ibarra L y col.…”
Section: Triage Strategies In Cervical Cancer Detection In Mexico: Mementioning
confidence: 99%
“…15 The institutional review boards of PATH, Cancer Institute and Hospital, Chinese Academy of Medical Sciences (CICAMS) and US National Cancer Institute approved the study.…”
Section: Populationmentioning
confidence: 99%