1980
DOI: 10.3177/jnsv.26.507
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An evaluation of a modified erythrocyte transketolase assay for assessing thiamine nutritional adequacy.

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Cited by 29 publications
(12 citation statements)
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“…Enzymatic methods are affected by preparation of hemolysates (8) and by storage (5,52) and concentrations of substrates and cofactors (35). These factors lead to a notable analytical variation between laboratories.…”
Section: Methodological Issuesmentioning
confidence: 99%
“…Enzymatic methods are affected by preparation of hemolysates (8) and by storage (5,52) and concentrations of substrates and cofactors (35). These factors lead to a notable analytical variation between laboratories.…”
Section: Methodological Issuesmentioning
confidence: 99%
“…41 Vitamin B 1 deficiency can be confirmed by assessing the vitamin B 1 pyrophosphate effect in erythrocyte transketolase studies. 43 The clinical constellation coupled with the response to administration of parenteral thiamine, especially with the features of the encephalopathy, may prove sufficiently diagnostic. Additionally, magnetic resonance imaging of the brain may show characteristic abnormalities, in particular, hyperintense signal abnormalities on T2-weighted images in the dorsomedial thalamic nuclei, periaqueductal gray matter, and mammillary bodies.…”
Section: Vitamin B 1 Deficiencymentioning
confidence: 99%
“…Thiamine deficiency can be confirmed by assessing the thiamine pyrophosphate effect in erythrocyte transketolase studies (Boni et al, 1980). The clinical constellation coupled with the response to parenteral thiamine, especially with the features of the encephalopathy, may prove sufficiently diagnostic.…”
Section: Neurologic Complications Of Bariatric Surgerymentioning
confidence: 99%