An ESIPT-Based Fluorescence Probe for Colorimetric, Ratiometric, and Selective Detection of Phosgene in Solutions and the Gas Phase

Abstract

Phosgene is a highly toxic substance that has become a serious potential threat to public health safety. A colorimetric and ratiometric fluorescence probe 1 for phosgene has been developed based on an ESIPT process. Both the visible colorimetric change from colorless to yellow and the fluorescent color change from blue to green (under 365 nm hand-held UV lamp) can be easily observed by the naked eye. Probe 1 has a high sensitivity and selectivity for phosgene in solutions and the gas phase. The mechanism for sensing by 1 was investigated by using high-resolution mass spectrometry and H NMR andC NMR spectroscopies.

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

“…Probe 60 could be incorporated into filter papers giving test strips that could be used for the qualitative detection of different concentrations of COCl 2 . 173…”

Derivatization and rapid GC-MS screening of chlorides relevant to the Chemical Weapons Convention in organic liquid samples

“…For these reasons on-site methods using sensors and probes to detect phosgene in air have continuously been developed. [18][19][20][21][22][23][24] Due to the instability of phosgene in air it has been collected in impingers and sorbent tubes containing a reagent to derivatize phosgene to a stable chemical. 25 Chemical reactions of phosgene are similar to those of acid chlorides and it reacts easily with alcohols.…”

Sensitive and Selective Detection of Phosgene, Diphosgene, and Triphosgene by a 3,4‐Diaminonaphthalimide in Solutions and the Gas Phase

“…In addition,t he phosgene-induced cyclization of cinnamic acids generates fluorescent coumarins, [7] and a meso-oxime-BODIPYs ensorc onverts into the meso-nitrile in the presence of phosgene. Reported fluorescentc hemosensorsw ith two structural features for phosgene detection:a)one amino groupo fo-diamino, [5] b) two amino groups, [10,11] linking at the fluorophore. Reported fluorescentc hemosensorsw ith two structural features for phosgene detection:a)one amino groupo fo-diamino, [5] b) two amino groups, [10,11] linking at the fluorophore.…”

“…The sensing reactiono fP hos-1 generates the sensing product urea with different ICT character,e xhibiting ar atiometric fluorescence response. [11] In this work, we have developeda no-diamino fluorescent sensor based on the strategy of Figure 1b,P hos-2, a1 ,8-naphthalimide with a3 ,4-diamine group as the actives ite, shown in Scheme 1. [11] In this work, we have developeda no-diamino fluorescent sensor based on the strategy of Figure 1b,P hos-2, a1 ,8-naphthalimide with a3 ,4-diamine group as the actives ite, shown in Scheme 1.…”

“… Reported fluorescent chemosensors with two structural features for phosgene detection: a) one amino group of o ‐diamino, b) two amino groups,, linking at the fluorophore.…”