An erythematous nodule on the eyelid

Mitra, Arijit; Ramnath, Raina Devi; Nicholson, Steven; Yung, Anthony

doi:10.1111/j.1365-2230.2007.02443.x

Cited by 2 publications

(13 citation statements)

References 5 publications

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“…The prognosis is grave with a recently reported 5-year local recurrence rate of 84% and the 5-year survival rate range from 12% to 34%3,4. Previously, our patient was treated for a primary angiosaroma of the right forehead with a surgical resection followed by a radiation therapy 3 years ago, and the tumor recurred on the right upper eyelid that was remote from the site of the previous surgery, not the right forehead where the primary angiosarcoma developed.…”

Section: Introductionmentioning

confidence: 76%

“…Angiosarcomas are rare malignant tumors arising from the vascular or the lymphatic endothelium and comprise 2% of all soft tissue sarcomas3. They can occur in a variety of sites, but 60% of the cases arise within the skin or the superficial soft tissues3.…”

Section: Discussionmentioning

confidence: 99%

“…They can occur in a variety of sites, but 60% of the cases arise within the skin or the superficial soft tissues3. The majority of these tumors arise in the head and the neck area and, rarely had an isolated eyelid involvement been reported3,4,5,6.…”

Section: Discussionmentioning

confidence: 99%

“…It develops de novo in most cases although it has also been reported to arise after an irradiation of some vascular tumors or from a persistent chronic lymphedema in the extremities (Stewart-Treves syndrome)3,5.…”

Section: Discussionmentioning

confidence: 99%

“…These are usually asymptomatic but may cause bleeding intermittently, become edematous, or cause pain. The skin lesions are usually red or blue, although they are occasionally tan or resemble a normal skin color3,4,5. Because they are often poorly defined, it is difficult to determine the the extent of the tumor.…”

Section: Discussionmentioning

confidence: 99%

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A Recurrent Angiosarcoma Isolated to the Eyelid without the Recurrence on the Primary Lesion of the Forehead

Kim

Kang

2014

Ann Dermatol

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Angiosarcoma is a highly malignant vascular tumor of endothelial origin. Initially, a cutaneous manifestation presents as a singular or multifocal bruise-like patches on the skin, most frequently on the face, the scalp or the neck regions. On progression, the lesions become violaceous, and ill-defined spongy nodular tumors appear. Our patient was a 71-year-old man with a previous history of angiosarcoma on the right forehead and was treated with an excision and local radiation 3 years ago. Several months after the treatment, a dark brownish to violaceous patch with edema arose from the right upper eyelid and spread out to the lower eyelid. Clinically, an ecchymosis caused by trauma or other hemangioma was suspected more than a recurrent angiosarcoma. Histopathologic examinations including immunohistochemical studies were consistent with cutaneous angiosarcoma. Herein, we report a rare case of a recurrent isolated angiosarcoma without the recurrence of a primary lesion.

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Section: Introductionmentioning

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A Recurrent Angiosarcoma Isolated to the Eyelid without the Recurrence on the Primary Lesion of the Forehead

Kim

Kang

2014

Ann Dermatol

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The Eyelid Angiosarcoma: A Systematic Review of Characteristics and Clinical Course

Hwang

Shin

Lee

et al. 2022

JCM

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A systematic search for eyelid angiosarcoma was performed from inception to December 2020 in Medline, EMBASE, and the Cochrane databases. Forty two eyelid angiosarcoma cases in 32 articles were analyzed. Eyelid angiosarcomas showed an incidence peak in the eighth decade of life, and was reported more frequently in Caucasian males. Eyelid angiosarcomas were associated with a mortality rate of 26.2%, a recurrence rate of 14.3%, and a cure rate of 45.2%. Four years event-free survival (EFS) rate was 36.0%, with median EFS of 36 months. Eyelid angiosarcomas with bilateral involvement or metastasis showed higher mortality and recurrence rates than unilateral eyelid invasion cases. In the prognosis analysis according to treatment modalities, the mortality and recurrence rates were the lowest in patients who underwent surgical excision. The 4-year EFS probability in a group with surgical excision was 60.6%, but in a group without surgical excision it was 30.3%. A total of 45.2% of the cases was misdiagnosed and 21.4% of the cases could not be correctly diagnosed with the first biopsy trial. The prognosis for eyelid angiosarcomas was better than that of angiosarcomas invading the face and scalp. Surgical excision was the most important treatment modality; thus, should be considered as the first treatment of choice.

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An erythematous nodule on the eyelid

Abstract: Figure 1 An erythematous nodule with oedema on the eyelid.

Cited by 2 publications

References 5 publications

A Recurrent Angiosarcoma Isolated to the Eyelid without the Recurrence on the Primary Lesion of the Forehead

A Recurrent Angiosarcoma Isolated to the Eyelid without the Recurrence on the Primary Lesion of the Forehead

The Eyelid Angiosarcoma: A Systematic Review of Characteristics and Clinical Course

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