An epidemiological survey of vulvovaginal candidiasis in Italy

Corsello, S; Spinillo, Arsenio; Osnengo, G; Penna, Carlo; Guaschino, Secondo; Beltrame, Anna; Blasi, Nicola; Festa, Antonio

doi:10.1016/s0301-2115(03)00096-4

Cited by 143 publications

(130 citation statements)

References 22 publications

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“…10,11,18 In HIV-uninfected patients, our data was similar to other studies performed in Brazil, which describe the prevalence of C. albicans isolated in vaginal samples ranging from 60% to 80% 19,20 and in other countries where the prevalence of C. albicans in vaginal samples ranges between 80% to 90%. 1,11,21,22 A higher diversity of non-albicans species was found in HIV-infected patients compared to uninfected controls. C. glabrata was the most frequent non-albicans species isolated in HIV-infected patients, followed by C. parapsilosis.…”

Section: Discussionmentioning

confidence: 99%

Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil

Oliveira¹,

Mascarenhas²,

Lacroix³

et al. 2011

Braz J Infect Dis

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Background: Vulvovaginal candidiasis (VVC) is the second most common vaginal infection. HIV-infection is a risk factor for this infection. Objective: To determine the frequency of VVC and to describe the main Candida species isolated and their susceptibility to antifungal drugs in HIV-infected patients, compared to HIV-uninfected women in Salvador, Brazil. Methods: Cross-sectional study including a group of 64 HIV-infected women and 76 uninfected women, followed up at the AIDS reference center and at the Gynecological Clinic of Escola Bahiana de Medicina e Saúde Pública (Salvador, Bahia, Brazil). Results: Frequency of Candida spp. was higher in HIV-infected women (29.7%) than in HIV-uninfected controls (14.5%) (p = 0.02). The odds ratio value for vulvovaginal candidiasis in HIV-infected patients was 2.6 (95% CI: 1.07 -6.32 p = 0.03). Candida albicans was the most commonly isolated species in both HIV-infected (52.3%) and uninfected women (85.7%), followed by C. parapsolis in 17.6% and 14.3%, respectively. In HIV-infected women, C. glabrata, C. parapsilosis, and a coinfection of C. albicans and C. glabrata were also identified. There was no significant difference between Candida species isolated from the vaginal mucosa of women with VVC and colonization of the vaginal mucosa of HIV-infected and HIV-uninfected women. One C. glabrata isolate from an HIV-infected patient was resistant to fluconazole and other two isolates exhibited a dose-dependent susceptibility. Conclusion: Our results confirm a higher frequency of Candida spp. isolated from the vaginal mucosa of HIV-infected women and a broader spectrum of species involved. Only Candida glabrata isolates showed decreased susceptibility to fluconazole.

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Section: Discussionmentioning

confidence: 99%

Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil

Oliveira¹,

Mascarenhas²,

Lacroix³

et al. 2011

Braz J Infect Dis

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“…once or twice a year or at least once in their lifetime (Corsello et al, 2003). The clinical symptoms include itching, edema, erythema of the vulva, vaginal discharge of white clots and pain.…”

Section: Introductionmentioning

confidence: 99%

Molecular diagnosis of vaginal candidiasis by polymerase chain reaction (PCR) and random amplification polymorphism DNA (RAPD-PCR) in Babylon Province, Iraq

Zaidan¹,

Hadeel²

2014

Afr. J. Microbiol. Res.

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Most women suffer from severe vaginal candidiasis caused by Candida spp. Vaginal infections represent a second type of common disease. This infection occurs commonly in married and pregnant women and immunocompromised patients. This study aimed to survey, isolate and diagnose the vaginal Candida spp. using phenotypic and molecular assays. Candida isolates were recovered from patients attending main hospital in Babylon Province, Iraq from July 2011 to April 2012. Samples were subcultured on CHROMagar for preliminary identification of Candida isolates. Germ tube and chlamydospore formation were also performed to confirm identification. DNA of representative isolates was extracted for polymerase chain reaction (PCR) assays and analyzed using gel image patterns of bands for different isolates based on ultraviolet transilluminator band software. Results show that CHROMagar was a good tool for preliminary identification of Candida isolates. Molecular identification of PCR and random amplification polymorphism DNA (RAPD-PCR) assays were used to group the representative Candida isolates into different genetic patterns; phylogenetic tree was generated based on the information available in gel images. This study concludes that PCR and RAPD PCR assays confirmed more the diagnosis of Candida isolates than culture on CHROMagar medium and other phenotypic tests.

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“…Oitenta por cento a 90% dos casos são devidos a C. albicans; 10% a 20%, a outras espécies chamadas não-C. albicans (C. tropicalis, C. glabrata, C. krusei, C. parapsilosis, C. pseudotropicalis, C. lusitaniae). C. glabrata é a segunda espécie em freqüência nas CVV (12,13,50,58) . Porém, leveduras de outros gêneros também podem causar essa infecção: Saccahromyces cerevisiae, Rhodutorula sp.…”

Section: Candidíase Vulvovaginalunclassified

“…A CVV representa 20% a 25% dos corrimentos vaginais de natureza infecciosa, precedida apenas pela vaginose bacteriana (12) . Na Europa, é a primeira causa de vulvovaginite (68) .…”

Section: Candidíase Vulvovaginalunclassified

“…Isso é particularmente verdade para as infecções por Candida, especialmente por C. albicans, que se apresentava como comensal, mas que, com as defesas comprometidas do indivíduo, se instala, invade tecidos e provoca danos. Concomitantemente, tem sido observada uma sensível elevação na freqüência de candidíase vulvovaginal (CVV) nos últimos anos, o que torna esse diagnóstico cada vez mais comum em ginecologia (12,68) . Além de fatores inerentes ao hospedeiro, tem sido postulado que existem diferenças na patogenicidade de isolados de Candida sp.…”

Section: Introductionunclassified

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Candidíase vulvovaginal: fatores predisponentes do hospedeiro e virulência das leveduras

Álvares¹,

Svidzinski²,

Consolaro³

2007

J. Bras. Patol. Med. Lab.

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; Márcia Edilaine Lopes Consolaro 3Introdução: Leveduras do gênero Candida são patógenos oportunistas freqüentemente isolados das superfícies mucosas de indivíduos normais, mas podem levar ao desenvolvimento de infecções denominadas candidíases, que variam desde lesões superficiais até infecções disseminadas. Objetivos: Ampliar os conhecimentos sobre candidíase vulvovaginal (CVV: infecção de vulva e vagina, causada por leveduras comensais que habitam a mucosa vaginal) e candidíase vulvovaginal recorrente (CVVR: ocorrência de quatro ou mais episódios de CVV no período de 12 meses), bem como caracterizar e abordar o ponto de vista das influências do hospedeiro e dos fatores de virulência dos agentes causais da infecção, principalmente C. albicans, visando identificar a sua importância nessa patologia. Tanto fatores predisponentes locais como sistêmicos do hospedeiro podem contribuir para a invasão por Candida sp. Sua intensa multiplicação no canal vaginal é favorecida por uma série de fatores predisponentes abordados nesta revisão. Também tem sido postulado que existem diferenças na patogenicidade de isolados de Candida sp., não sendo o fungo apenas um participante passivo no processo infeccioso; com isso vários fatores de virulência têm sido propostos e são descritos. Discussão e conclusões: Este artigo de revisão bibliográfica buscou atualizar os profissionais da área da saúde em relação a CVV, CVVR, aspectos predisponentes do hospedeiro e virulência dos agentes causais, que são pouco conhecidos. Assim, a atualização e o conhecimento de conceitos básicos e clínicos relacionados com essa patologia são muito importantes para auxiliar o seu manejo pelos profissionais da área. abstract resumo Introduction: Vulvovaginal candidiasis (VVC) is a vulva and vagina infection caused by comensal yeasts that inhabit the vaginal mucosa and eventually become patogenic, depending on host conditions. Eighty percentto 90% of the infections are due to C. albicans, and 10% to 20% to other species called non-C. albicans (C. tropicalis, C. glabrata, C. krusei, C. parapsilosis, C. pseudotropicalis, C. lusitaniae

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An epidemiological survey of vulvovaginal candidiasis in Italy

Cited by 143 publications

References 22 publications

Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil

Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil

Molecular diagnosis of vaginal candidiasis by polymerase chain reaction (PCR) and random amplification polymorphism DNA (RAPD-PCR) in Babylon Province, Iraq

Candidíase vulvovaginal: fatores predisponentes do hospedeiro e virulência das leveduras

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