An epidemiological analysis of a canine-biopsies database compiled by a diagnostic histopathology service

Richards, Heather G.; McNeil, P. E.; Thompson, H.; Reid, S. W. J.

doi:10.1016/s0167-5877(01)00211-2

Cited by 39 publications

(51 citation statements)

References 16 publications

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“…The differences in tumor prevalence were significant (P = 0.00000427). Skin tumors were the most prevalent, mainly appearing in older animals, in agreement with other studies (Dobson et al 2002, Kelsey et al 1998, Pires et al 2003, Richards et al 2001. This is possibly due to the skin being the tissue most exposed to various environmental factors that can trigger tumor development (Vail and Withrow 2007).…”

Section: Results and Discusionsupporting

confidence: 87%

Prevalence of tumors in dogs from the municipality of Toluca, México, from 2002 to 2008

et al. 2013

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RESUMENLos estudios epidemiológicos del comportamiento tumoral pueden generar datos importantes sobre la aparición espontánea de neoplasias en animales. En Toluca se carecen de datos epidemiológicos sobre oncología veterinaria. Este estudio de prevalencia de tumores está basado en la población total de perros con dueño del municipio de Toluca y es el primero que se realiza en México. Se recibieron en el Laboratorio del CIESA, durante el periodo 2002/2008 un total de 172 tumores y la prevalencia estimada fue de 1.23/1000 perros con dueño. La prevalencia en hembras fue de 1.37 y en machos de 1.08. La frecuencia de tumores por grupos de edad fue: 59.3% en perros de 7-15 años, 33.7% en perros de 2 a menores de 7 años y el 7% en perros menores de 2 años. La raza que presentó frecuentemente tumoraciones fue el Labrador (18.4%). Los tumores más prevalentes fueron los tumores de piel con una prevalencia de 0.65, seguido de los tumores de glándula mamaria (0.24). Estos resultados muestran que la edad podría estar relacionada en la aparición de tumores malignos y que el factor UV podría relacionarse con la presencia de algunos tipos de tumores cutáneos. Este estudio contribuye al entendimiento epidemiológico de los tumores en perros del municipio de Toluca, con el propósito de establecer el primer Registro de Tumores de perros en México.Palabras clave: perros, prevalencia de tumores, Toluca, México. SUMMARYThe purpose of this study was to estimate the prevalence of tumors in biopsies of owned dogs sent to the pathology laboratory from the municipality of Toluca. Tissue samples (n = 172) were received at CIESA laboratory from 2002 to 2008. The estimated prevalence was 1.23/1000 dogs, with values of 1.37 for bitches 1.08 for males. The frequency of tumors per age group was: 59.3% in dogs of 7-15 years old, 33.7% in dogs of 2-6 years old and 7% in dogs younger than 2 years old. Skin tumors were the most prevalent (0.65), followed by mammary gland tumors (0.24). These results suggested that age could be associated to the presence of malignant tumors, and that UV radiation could be associated to the appearance of certain types of skin tumors. This study contributes to the understanding of the epidemiology of tumors in dogs from Toluca, in order to establish the first registry of dog tumors in Mexico.

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Section: Results and Discusionsupporting

confidence: 87%

Prevalence of tumors in dogs from the municipality of Toluca, México, from 2002 to 2008

et al. 2013

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“…An age-dependent increase in incidence for the development of a neoplasm is in agreement with other studies [8,31,34]. Highest-peak-incidence was noted at a younger age in the current study than peakincidence of cancers in a study in Italy (>12 years) [31] but at a comparable age when compared with the study of Dobson [34], which is remarkable, considering the potential bias for younger animals of this last study due to different age-structure [23].…”

Section: Age Sex and Locationsupporting

confidence: 92%

“…Taking a potential sampling bias for the occurrence of tumours into account, since more common locations are also more easily clinically accessible [8], the most common locations of histological diagnosed tumours were skin and adnexa (Table 4) which was also found in earlier studies [12,17].…”

Section: Age Sex and Locationsupporting

confidence: 69%

“…Breeding from within a selected population of dogs can, in a relative short period of time, give rise to a clear change in phenotype which leads to breed development [1,2] but may also cause an increase in the occurrence of inherited diseases [3][4][5][6][7] such as cancer [8][9][10][11][12]. Clear evidence exists for a breed-related predisposition to specific cancers, like histiocytic sarcomas in Bernese Mountain dogs [10,13] and Flatcoated retrievers, [11] anal sac carcinomas in the English Cocker Spaniel [12,14] and hemangiosarcomas in German Shepherd dogs [15].…”

Section: Introductionmentioning

confidence: 99%

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A longitudinal study of ABC transporter expression in canine multicentric lymphoma

Zandvliet

Teske

Schrickx

et al. 2015

The Veterinary Journal

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Background: A genetic predisposition for certain tumour types has been proven for some dog breeds. Some studies have suggested that this may also be true for the Golden retriever breed. The present study aimed to examine a possible existence of a tumour (type) predisposition in the Dutch population of Golden retrievers by evaluating annual estimated incidence rates compared to incidence rates from previous publications. A second aim was to evaluate whether incidences of various tumours differed as related to the diagnostic method chosen, being either cytology or histology. Results: Tumours submitted to Utrecht University during the period 1998-2004 diagnosed either by means of cytology (n = 2,529) or histology (n = 2,124), were related to an average annual Dutch kennel club population of 29,304 Golden retrievers. Combining individual tumours from both the cytological and the histopathological data-set resulted in an annual estimated incidence rate of 2,242 for 100,000 dog-years at risk regarding tumour development in general. The most common cytological tumor diagnoses were 'fat, possibly lipoma' (35%), mast cell tumour (21%) and non-Hodgkin lymphoma (10%). The most commonly diagnosed tumours by histology were mast cell tumour (26%), soft tissue sarcomas (11%) and melanoma (8%). Both the cytological and histopathological data-sets, showed variation; in patient age distribution, age of onset and incidence of various tumours. Conclusion: Comparing our data with previous reports in non-breed-specified dog populations, the Golden retriever breed shows an increased risk for the development of tumours in general, as well as an increased risk for the development of specific tumour types, including the group of soft tissue sarcomas. Variations in age, location and incidence of various tumours were observed between the two data-sets, indicating a selection bias for diagnostic procedure.

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“…Interestingly, the current case was present in an animal of just 11 months old. On the other hand, it is stated that the boxer race has a higher susceptibil- ity for tumor formation [4,14]. RMS is a tumor derived from skeletal muscle, composed of anaplastic muscle cells, and is one of the malignant neoplasms seen in veterinary medicine.…”

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confidence: 99%

Aggressive Spindle Cell Rhabdomyosarcoma in an 11-Month-Old Boxer Dog

Roza

Amorim

Carneiro

et al. 2010

The Journal of Veterinary Medical Science

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ABSTRACT. Rhabdomyosarcoma (RMS) is a malignant neoplasm derived from mesenchymal tissue with a tendency toward myogenic differentiation associated with the embryogenesis of skeletal muscle. According to the histological features, it can be classified in embryonal, botryoid, alveolar, and pleomorphic, which usually correspond to clinical behavior and prognosis. The spindle cell (SCRMS) variant is a rare subtype of the embryonal RMS and is considered to be less aggressive lesion. The aim of the present paper is to report an unusual case of SCRMS in an 11-month-old male boxer dog diagnosed as extensive SCRMS that affected the frontal region of the skull. Due to the aggressive nature of the lesion and poor clinical prognosis the dog's owners preferred euthanasia as a treatment. A full postmortem examination was carried out. Microscopically, the lesion was composed of a highly cellular proliferation of spindle cells arranged in long and intersecting fascicles. After performing the immunohistochemical studies (HHF-35, smooth muscle actin, desmin and MyoD1), the present case was diagnosed as SCRMS.

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An epidemiological analysis of a canine-biopsies database compiled by a diagnostic histopathology service

Cited by 39 publications

References 16 publications

Prevalence of tumors in dogs from the municipality of Toluca, México, from 2002 to 2008

Prevalence of tumors in dogs from the municipality of Toluca, México, from 2002 to 2008

A longitudinal study of ABC transporter expression in canine multicentric lymphoma

Aggressive Spindle Cell Rhabdomyosarcoma in an 11-Month-Old Boxer Dog

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