An epidemiologic case-control study in a population with vitiligo

Barona, María Isabel; Arrunátegui, Adriana; Falabella, Rafael; Alzate, Alberto

doi:10.1016/0190-9622(95)91282-7

Cited by 102 publications

(94 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…5 With regard to the site of onset, the upper limbs were also the most frequently affected. They were also the most commonly affected site (77.9%) in an Indian study.…”

Section: Discussionmentioning

confidence: 99%

“…3.4 Average age of onset occurs around the second to the third decade of life. 5 Adults and children of both genders are equally affected, but some studies indicate a slight prevalence of cases among females, possibly due to greater psychosocial consequences caused by this skin condition; however, this 2.6 is not considered statistically significant because some studies show similar rates for both genders. 7 The site of onset and distribution of lesions differ according to age and region of the study population, but the most affected sites are, respectively, the head, limbs and trunk; the less affected sites are mucous membranes.…”

Section: Introductionmentioning

confidence: 96%

See 1 more Smart Citation

Perfil epidemiológico dos pacientes com vitiligo e sua associação com doenças da tireoide

Nunes

Esser

2011

An. Bras. Dermatol.

View full text Add to dashboard Cite

BACKGROUND: Vitiligo is considered the most frequent acquired hypomelanosis. Although its pathogenesis is uncertain, it is believed that autoimmune etiology is the most plausible. This theory is based on the coexistence of vitiligo with autoimmune diseases. Objectives: To describe the epidemiological profile of vitiligo patients and to estimate the prevalence of the association of vitiligo with autoimmune thyroid diseases. Methods: A cross-sectional study was conducted through analysis of the medical records of patients diagnosed with vitiligo in the AME-UNISUL Outpatient Clinic of Dermatology and at HU-UFSC. The clinical and laboratorial characteristics of these patients were assessed. Results: 85 medical records were evaluated; 56 patients were female, with a mean age of 37.14 years and mean onset age of 25.25 years. Vitiligo vulgaris occurred in 70.6%. Autoimmune thyroid diseases were found in 22.4%. Other autoimmune diseases were identified in 5.9%. Patients with positive thyroid autoantibodies showed a probability of extension of vitiligo greater than 25%. There was no statistical difference with regard to the clinical characteristics of vitiligo in patients with or without autoimmune thyroiditis with hormonal change. Conclusion: The findings of this study are similar to those obtained by other authors, showing that autoimmune thyroid diseases are more common in patients with vitiligo. Keywords: Autoimmunity; Thyroid diseases; Vitiligo Resumo: FUNDAMENTO: O vitiligo é considerado a hipomelanose adquirida mais frequente. Apesar de sua etiopatogenia ser incerta, acredita-se que a etiologia autoimune seja a mais plausível, teoria que se fundamenta na concomitância de vitiligo com doenças autoimunes. OBJETIVOS: Traçar o perfil epidemiológico dos pacientes com vitiligo e estimar a prevalência da associação de vitiligo com doenças autoimunes da tireoide. MÉTODOS: Efetuou-se um estudo transversal, analisando-se prontuários dos pacientes com diagnóstico de vitiligo atendidos no Ambulatório de Dermatologia AME-Unisul e do HU-UFSC. Avaliaram-se as características clínicas e laboratoriais desses pacientes. RESULTADOS: Foram avaliados 85 prontuários, sendo 56 do sexo feminino, com idade média de 37,14 anos e idade média de início de 25,25 anos. O vitiligo vulgar ocorreu em 70,6% dos casos. As doenças autoimunes da tireoide foram encontradas em 22,4% dos casos. Outras doenças autoimunes foram identificadas em 5,9% dos casos. Os pacientes com anticorpos antitireoidianos positivos revelaram uma probabilidade elevada de extensão do vitiligo maior que 25%. Não houve diferença estatística quanto às características clínicas do vitiligo em portadores ou não de tireoidite autoimune com alteração hormonal. CONCLUSÃO: Os resultados deste estudo são similares aos de outros autores, mostrando que as doenças autoimunes da tireoide são mais frequentes nos pacientes com vitiligo.

show abstract

“…5 With regard to the site of onset, the upper limbs were also the most frequently affected. They were also the most commonly affected site (77.9%) in an Indian study.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

Perfil epidemiológico dos pacientes com vitiligo e sua associação com doenças da tireoide

Nunes

Esser

2011

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

“…[7][8][9] Results of several independent epidemiological studies show that the KP occurs in most patients with vitiligo. [10][11][12] Its clinical relevance is not yet established, although it has been frequently postulated that the KP may indicate active disease. 5,13,14 However, no further data have been obtained to support this hypothesis.…”

mentioning

confidence: 99%

Association of the Köbner Phenomenon With Disease Activity and Therapeutic Responsiveness in Vitiligo Vulgaris

Njoo¹,

Das²,

Bos³

et al. 1999

Arch Dermatol

195

166

View full text Add to dashboard Cite

“…Barona et al [8] stated that the presence of a halo nevus indicates a risk factor of vitiligo progression and a prospective observational study suggest that non-segmental vitiligo-associated halo nevus affects age of onset and depigmentation pattern, and has a more frequent familial background of autoimmunity [9]. Moreover, patients with multiple non-segmented vitiligo with congenital melanocytic nevus had a higher frequency of halo nevi at distance, which suggests a relationship between vitiligo and halo nevus [9,10].…”

Section: Concurrent Vitiligo In Congenital Halo Nevusmentioning

confidence: 99%

Halo Nevus Arising from Congenital Melanocytic Nevus Featuring an Early Onset Vitiligo

et al. 2017

View full text Add to dashboard Cite

An epidemiologic case-control study in a population with vitiligo

Cited by 102 publications

References 26 publications

Perfil epidemiológico dos pacientes com vitiligo e sua associação com doenças da tireoide

Perfil epidemiológico dos pacientes com vitiligo e sua associação com doenças da tireoide

Association of the Köbner Phenomenon With Disease Activity and Therapeutic Responsiveness in Vitiligo Vulgaris

Halo Nevus Arising from Congenital Melanocytic Nevus Featuring an Early Onset Vitiligo

Contact Info

Product

Resources

About