An Envenoming Syndrome from Massive Vespa Stings Induces Multiple Organ Failure

Chen, Tse-Hao; Liao, Wan-Chun; Chen, Chien‐Sheng; Lin, Po‐Chen; Wu, Meng‐Yu

doi:10.3390/insects11040219

Cited by 7 publications

(4 citation statements)

References 15 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hyaluronidase hydrolyzes the hyaluronic acid between cells, probably facilitating a smooth entry of toxins into body tissues, possibly exacerbating local inflammation. 6 In this study, the patient had normal platelets on admission, which decreased to 42 × 10 9 ·L −1 on Day 8 of admission. A report in India demonstrated that thrombocytopenia was found in patients stung by wasps, and the authors suggested that thrombocytopenia is a direct result of wasp venom’s effect on platelets.…”

Section: Discussionmentioning

confidence: 47%

Hybrid Blood Purification in the Treatment of Multiple Organ Dysfunction Syndrome Following a Wasp Attack

Liu

Zhan

Ran

et al. 2022

Wilderness & Environmental Medicine

View full text Add to dashboard Cite

Severe wasp sting symptoms can progress rapidly, often causing multiple organ dysfunction syndrome (MODS) and, in some cases, even death. Early and comprehensive treatment is needed to avoid these outcomes. Here, we report the case of a patient with MODS due to severe wasp stings. The patient received conventional treatment combined with glucocorticoids, plasma exchange, hemoperfusion, and continuous renal replacement therapy and had a successful recovery. MODS is a serious potential complication of wasp stings. Early local wound treatment, antiallergy interventions, antishock therapy, fluid replacement, glucocorticoid administration, and blood purification treatments are required to treat MODS secondary to wasp stings. Our results suggest that a hybrid blood purification method involving plasma exchange combined with hemoperfusion and continuous renal replacement therapy is more clinically effective than the single blood purification method. Early use of high-dose glucocorticoids combined with a hybrid blood purification treatment method had a positive effect in managing our patient and may improve the prognosis of other patients with MODS.

show abstract

Section: Discussionmentioning

confidence: 47%

Hybrid Blood Purification in the Treatment of Multiple Organ Dysfunction Syndrome Following a Wasp Attack

Liu

Zhan

Ran

et al. 2022

Wilderness & Environmental Medicine

View full text Add to dashboard Cite

show abstract

“…A decrease in hepatic synthetic functions can also be observed, although the coagulopathy is contributed by DIC. A significant proportion will progress to acute fulminant hepatic failure [51] while other patterns of hepatic injury such as Reye syndrome have also been observed [52].…”

Section: Hepatic Effectsmentioning

confidence: 99%

Clinical manifestations of wasp stings: a case report and a review of literature

Ruwanpathirana

Priyankara²

2022

Trop Med Health

View full text Add to dashboard Cite

Background Wasp stinging, a neglected tropical entity can have a myriad of local and systemic effects. We present a case of multi-organ injury following multiple wasp stings and a review of literature on the systemic manifestations of wasp stings. Case presentation A 48-year-old Sri Lankan male who suffered multiple wasp stings, developed an anaphylactic shock with respiratory failure, which was treated with adrenaline and mechanical ventilation. Within the next 2 days the patient developed acute fulminant hepatitis, stage III acute kidney injury, rhabdomyolysis, haemolysis and thrombocytopenia. The patient was treated in the intensive care unit with ionopressors and continuous renal replacement therapy (CRRT). Haemoadsorbant therapy was used in adjunct with CRRT. There was a gradual recovery of the organ functions over the 1st week. However, the patient succumbed to fungal sepsis on the 16th day despite treatment. We conducted a literature review to identify the various clinical manifestations of wasp stinging. Wasp venom contains enzymes, amines, peptides and other compounds. These proteins can cause type 1 hypersensitive reactions ranging from local skin irritation to anaphylactic shock. Furthermore, the toxins can cause direct organ injury or delayed hypersensitivity reactions. The commonly affected organs are the kidneys, liver, and muscles. The effect on the haematological system manifests as coagulopathy and/or cytopenia. The heart, nervous system, lungs, intestines and skin can be affected rarely. Treatment is mainly supportive. Conclusion In conclusion, wasp envenomation can result in multi-organ injury and attention should be paid in doing further research and establishing evidence-based treatment practices.

show abstract

“…El principal componente del veneno de las abejas es la melitina, que desorganiza las membranas celulares, libera aminas biogénicas, altera la permeabilidad celular y genera liberación de histamina (causante del dolor local y de las reacciones anafilácticas) 6 . También induce liberación de catecolaminas, que en conjunto con la fosfolipasa A2 causa hemólisis intravascular, lo que puede ocasionar rabdomiólisis y falla renal aguda por vasoconstricción renal, formación de depósitos de mioglobina intratubular y citotoxicidad directa de la mioglobina a los túbulos renales; complicaciones encontradas en casos con múltiples picaduras, por lo general más de 500 1,7 .…”

Section: Introductionunclassified

Falla renal aguda por rabdomiólisis; reporte de caso en un paciente pediátrico con múltiples picaduras de abejas

Mendoza-Vega¹,

Guillestegui-Rodríguez²,

Pasos-Solís³

2022

REIE

View full text Add to dashboard Cite

An Envenoming Syndrome from Massive Vespa Stings Induces Multiple Organ Failure

Cited by 7 publications

References 15 publications

Hybrid Blood Purification in the Treatment of Multiple Organ Dysfunction Syndrome Following a Wasp Attack

Hybrid Blood Purification in the Treatment of Multiple Organ Dysfunction Syndrome Following a Wasp Attack

Clinical manifestations of wasp stings: a case report and a review of literature

Falla renal aguda por rabdomiólisis; reporte de caso en un paciente pediátrico con múltiples picaduras de abejas

Contact Info

Product

Resources

About