An Enhanced Method for Full-Inversion-Based Ultrasound Elastography of the Liver

Aboutaleb, Mohamed; Kheirkhah, Niusha; Samani, Abbas; Sadeghi‐Naini, Ali

doi:10.1109/embc48229.2022.9871656

Cited by 3 publications

(1 citation statement)

References 41 publications

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“…Conventional ultrasound has always been the first choice for the clinical screening of liver cancer, and can effectively visualize the size, number, position, internal echo and other parameters, in liver cancer lesions. However, ultrasound can be affected by a range of factors, including acoustic window, gas, body position and angle; thus, conventional ultrasound is of limited value for the diagnosis of liver cancer [12,13]. Research has shown that CEUS can comprehensively and objectively reflect blood perfusion in new vessels and micro-vessels within tumors, thus improving the clinical diagnosis of liver cancer [14][15][16].…”

Section: Discussionmentioning

confidence: 99%

The analysis of contrast-enhanced ultrasound features of the liver in male patients with liver cancer and unhealthy life habits under 50 years-of-age

2023

Journal of Men's Health

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To analyze the contrast-enhanced ultrasound (CEUS) features of livers in male patients under 50 years-of-age with liver cancer and unhealthy life habits. A total of 89 male patients with liver cancer and unhealthy life habits were included in the observation group (all of these patients were first diagnosed with liver cancer when they were <50 years-of-age) and 60 male patients of the same age with benign liver lesions admitted during the same period were included in the control group. All patients had undergone CEUS examination. We summarized and compared the features of liver CEUS from patients in the two groups and analyzed the relationship between liver CEUS results and pathological features. The time to enhancement, enhancement duration and the clearance time of cancer tissues were all significantly shorter in patients from the observation group than those in the control group (p < 0.05). Enhancement patterns of cancer tissues and benign lesion tissues in patients in the observation group were significantly higher than those in the control group (p < 0.05). Cancerous tissues had fast wash-in and fast wash-out features (93.2%), while benign lesions had slow wash-in and slow wash-out features (60.00%). The proportion of patients with microvascular invasion (MVI)-positive lesions showing more than a 15% increase in maximum diameter was significantly larger than those with MVI-negative lesions (p < 0.05). The differences in enhancement features between liver cancer lesions with various differentiation grades in the portal phase and the delayed phase were statistically significant (p < 0.05). Our findings show that CEUS has high clinical value for diagnosing liver cancer and can be used to judge the MVI status and differentiation grade of liver cancer lesions, thus providing a reference for diagnosing liver cancer and its severity.

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Section: Discussionmentioning

confidence: 99%

The analysis of contrast-enhanced ultrasound features of the liver in male patients with liver cancer and unhealthy life habits under 50 years-of-age

2023

Journal of Men's Health

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Radiomics and machine learning analysis by computed tomography and magnetic resonance imaging in colorectal liver metastases prognostic assessment

Granata,

Fusco,

De Muzio

et al. 2023

Radiol med

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Colorectal liver metastases patients prognostic assessment: prospects and limits of radiomics and radiogenomics

Granata

Fusco

Setola

et al. 2023

Infect Agents Cancer

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In this narrative review, we reported un up-to-date on the role of radiomics to assess prognostic features, which can impact on the liver metastases patient treatment choice. In the liver metastases patients, the possibility to assess mutational status (RAS or MSI), the tumor growth pattern and the histological subtype (NOS or mucinous) allows a better treatment selection to avoid unnecessary therapies. However, today, the detection of these features require an invasive approach. Recently, radiomics analysis application has improved rapidly, with a consequent growing interest in the oncological field. Radiomics analysis allows the textural characteristics assessment, which are correlated to biological data. This approach is captivating since it should allow to extract biological data from the radiological images, without invasive approach, so that to reduce costs and time, avoiding any risk for the patients. Several studies showed the ability of Radiomics to identify mutational status, tumor growth pattern and histological type in colorectal liver metastases. Although, radiomics analysis in a non-invasive and repeatable way, however features as the poor standardization and generalization of clinical studies results limit the translation of this analysis into clinical practice. Clear limits are data-quality control, reproducibility, repeatability, generalizability of results, and issues related to model overfitting.

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An Enhanced Method for Full-Inversion-Based Ultrasound Elastography of the Liver

Cited by 3 publications

References 41 publications

The analysis of contrast-enhanced ultrasound features of the liver in male patients with liver cancer and unhealthy life habits under 50 years-of-age

The analysis of contrast-enhanced ultrasound features of the liver in male patients with liver cancer and unhealthy life habits under 50 years-of-age

Radiomics and machine learning analysis by computed tomography and magnetic resonance imaging in colorectal liver metastases prognostic assessment

Colorectal liver metastases patients prognostic assessment: prospects and limits of radiomics and radiogenomics

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