An endoscopic method to study the relationship between bowel habit and motility of the ascending and sigmoid colon

Colonic Diverticular Disease: Abnormalities of Neuromuscular Function

“…Similar abnormalities (mostly consisting of a significant increase of motor activity both basally and/or in response to eating, compared to controls) were subsequently confirmed by other authors by means of electromyographic [11,12] or manometric studies [13,14,15], and were also documented in right sided diverticular disease of the colon [16,17]. However, these findings could not be universally replicated, and other authors failed in demonstrating significant differences in rectosigmoid motor activity between controls and patients with CDD [18,19,20,21].…”

Comparison of etiology of right-sided diverticula in Japan with that of left-sided diverticula in the West

“…Sasaki [106] and Sasaki et al [107] reported that the intraluminal pressure is higher in the ascending colon with right-sided diverticular disease than that in the sigmoid colon. These studies strongly suggest that intraluminal pressure causes the development of right-sided diverticula in Japan.…”

“…Western reports generally use two methods, i.e., measuring the distance of string from mouth to anus, and by postmortem survey [112,113,114,115,116,117,118,119]; in contrast, Japanese reports determine the length of the large intestine by radiographs with barium enema [110,111]. As mentioned above, Sugihara et al [105] and Sasaki et al [107] have suggested that intraluminal pressure causes the development of right-sided diverticula in Japan. Furthermore, diverticula in Japanese patients generally first develop on the right-sided colon and extend to the left-sided colon with aging.…”

Limited evidence of abnormal intra‐colonic pressure profiles in diverticular disease – a systematic review

“…Of the 1849 articles identified based on the above search strategy 23 full text articles were reviewed. Of these 13 were excluded because of a lack of control group , inclusion of diagnoses other than sigmoid diverticulosis , insufficient details to extract or calculate the necessary data from the published results , a retrospective study design and technique other than manometry used to study gut motility .…”