An Enantioselective Total Synthesis of (+)‐Ricciocarpin A.

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Reductive Cyclization of o-Nitroarylated-α,β-unsaturated Aldehydes and Ketones with TiCl3/HCl or Fe/HCl Leading to 1,2,3,9-Tetrahydro-4H-carbazol-4-ones and Related Heterocycles

“…The filtrate was concentrated under reduced pressure, and the residue so obtained was subjected to flash column chromatography (silica, 1:7 v/v ethyl acetate/40−60 petroleum ether elution). Concentration of the appropriate fractions (R f = 0.2) then gave compound 9 6 (1.29 g, 91%) as a clear, yellow oil. 1 H NMR (400 MHz, CDCl 3 , δ): 7.45 (broad s, 1H), 2.67 (t, J = 6.9 Hz, 2H), 1.92 (t, J = 6.9 Hz, 2H), 1.18 (broadened s, 6H).…”