Under the background of digital economy, informatization has become the basic condition for the development and transformation of textile and garment enterprises. Aiming at the influencing factors of textile and apparel enterprise informatization, based on TOE framework (i.e., technology-organization-environment framework), The significant mediating role of inter-firm competition factors at the inter-organizational level in the influence of technology-level and intra-organizational-level factors on the informatization of textile and apparel firms is proposed and verified. It further enriches the influence mechanism of various factors on the Informa ionization of textile and garment enterprises. The policy support is introduced into the model as a moderating variable, and the results show that the policy support only has a significant positive moderating effect on the impact of industrial collaboration on the informatization of textile and apparel enterprises.