An emerging trend in Novel Psychoactive Substances (NPSs): designer THC
Cristian Caprari,
Elena Ferri,
Maria Angela Vandelli
et al.
Abstract:Since its discovery as one of the main components of cannabis and its affinity towards the cannabinoid receptor CB1, serving as a means to exert its psychoactivity, Δ9-tetrahydrocannabinol (Δ9-THC) has inspired medicinal chemists throughout history to create more potent derivatives. Initially, the goal was to synthesize chemical probes for investigating the molecular mechanisms behind the pharmacology of Δ9-THC and finding potential medical applications. The unintended consequence of this noble intent has been… Show more
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