An elusive consensus definition of sarcopenia impedes research and clinical treatment: A narrative review

Coletta, Giulia; Phillips, Stuart M.

doi:10.1016/j.arr.2023.101883

Cited by 62 publications

(43 citation statements)

References 89 publications

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“…The presence of sarcopenia was evaluated according to the EWSGOP 2 Criteria (Table 1). 4 One test that measures lower extremity muscle strength in elderly patients is the 30‐s sit‐stand test. However, we did not prefer the chair test because this test has not been well studied in young, middle‐aged patients, and we observed that the walking test was more practical in our previous studies.…”

Section: Methodsmentioning

confidence: 99%

“…EWGSOP (European Working Group on Sarcopenia in Older People) was established in 2009 and consisted of the members of many different institutions (e.g., EUGMS, ESPEN, IANA, IAGG‐ER) to create a consensus on the definition of sarcopenia. The report published in 2010 emphasized not only the loss of muscle mass but also a decrease in muscle functions; in other words, performance must also be affected for the diagnosis of sarcopenia, and the definition was updated in 2018 4 …”

Section: Introductionmentioning

confidence: 99%

“…The report published in 2010 emphasized not only the loss of muscle mass but also a decrease in muscle functions; in other words, performance must also be affected for the diagnosis of sarcopenia, and the definition was updated in 2018. 4 Muscle functions must be normal or close to normal for an individual to sustain daily life and to be self-sufficient. Sarcopenia causes comorbid conditions such as decreases in the individual's quality of life, difficulty sustaining life without being dependent on others, sudden falls, and an increase in the possibility of fractures that make them bedridden because it also causes muscle dysfunction.…”

Section: Introductionmentioning

confidence: 99%

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The frequency of sarcopenia has increased in patients with glomerulonephritis

et al. 2023

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Aim: Sarcopenia is defined as the loss of muscle mass and muscle strength, and its frequency increases in kidney patients. However, sarcopenia frequency in patients with glomerulonephritis is unknown. The present study aimed to investigate the frequency of sarcopenia in patients with glomerulonephritis and compare the results with the healthy population for the first time in the literature. Patients and Methods: A total of 110 participants, including 70 patients previously diagnosed with glomerulonephritis and 40 healthy individuals, were included in the study. The diagnosis of sarcopenia was made based on the EWSGOP 2 Criteria.Results: The mean age of the glomerulonephritis patients group was 39.3 ± 1.5. In the anthropometric measurements of the patients, walking speed was low in 50 patients (71.4%), muscle strength was decreased in 44 patients (62.9%), and sarcopenia was detected in 10 patients (14.3%) according to the EWGSOP 2 Criteria.Considering the anthropometric measurements of the control group, sarcopenia was not detected in any of the subjects according to the EWGSOP 2 Criteria. Conclusion:The result of the present study revealed that the rate of sarcopenia was significantly higher in glomerulonephritis patients compared to the healthy population and that sarcopenia can also be observed even in middle age in this population.We think it would be beneficial for clinicians treating glomerulonephritis to be more careful regarding sarcopenia and keep these parameters in mind during treatment.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The frequency of sarcopenia has increased in patients with glomerulonephritis

et al. 2023

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“…Sarcopenia is an age-related skeletal muscle disorder characterized by a progressive and generalized decrease in muscle mass and function. 1 A previous study noted that muscle mass decreases at a rate of approximately 8% per decade from 40 years-of-age, and the decrease rate increases with advancing age and it accelerates to 15% per decade beyond 70 years-of-age. 2 Originally focused on the decline of muscle mass, the definition of sarcopenia has evolved to characterize a decrease of muscle strength, particularly physical performance, through a number of working group definitions, such as that of the recent Asian Working Group for Sarcopenia 2019 (AWGS 2019).…”

Section: Introductionmentioning

confidence: 94%

“…Sarcopenia is an age‐related skeletal muscle disorder characterized by a progressive and generalized decrease in muscle mass and function 1 . A previous study noted that muscle mass decreases at a rate of approximately 8% per decade from 40 years‐of‐age, and the decrease rate increases with advancing age and it accelerates to 15% per decade beyond 70 years‐of‐age 2 .…”

Section: Introductionmentioning

confidence: 99%

Association of possible sarcopenia with major chronic diseases and multimorbidity among middle‐aged and older adults: Findings from a national cross‐sectional study in China

Zhao,

Zhang,

et al. 2023

Geriatrics Gerontology Int

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AimThis study investigated the prevalence of possible sarcopenia (PSA) in a large sample of middle‐aged and older adults, and determined the association between PSA, major chronic diseases and the number of chronic diseases.MethodsA total of 14 917 adults aged ≥40 years were included in the analysis. The handgrip strength and the five‐time chair stand test were used to assess PSA. The participants' major chronic diseases were divided into 14 categories. Four categories were created based on the participants' number of chronic illnesses: 0, 1, 2 and ≥3.ResultsThe present study found an overall prevalence of PSA of 23.6% among Chinese middle‐aged and older adults aged ≥40 years, with the risk increasing with advancing age. PSA was significantly associated with most categories of chronic diseases and multimorbidity. The closely independent associations were obtained for stroke; emotional, nervous or psychiatric problems; chronic lung disease, asthma, heart disease, hypertension and arthritis or rheumatism. Compared with participants with 0 chronic disease, those with two or more chronic diseases had higher odds for PSA. However, the association between PSA and the number of chronic diseases varied in different sex and age groups.ConclusionsThe findings suggest that PSA is associated with major chronic diseases among middle‐aged and older adults. People with two or more chronic diseases have a greater likelihood of PSA compared with those without chronic diseases, and the association between PSA and the number of chronic diseases largely depended on sex and age. Geriatr Gerontol Int 2023; ••: ••–••.

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