The quotient of the function difference over the variable increment is evaluated in 1+n finite dimensional imaginary scator algebra. A distinctive property of the scator product is that it is commutative albeit not distributive over addition. In S 1+n , a subset of R 1+n where the product is defined, all the elements have inverse provided that zero is excluded. The quotient of scators and their differential limit can thus be defined in this subset, establishing the notion of scator differentiability. The necessary conditions that a scator holomorphic function must satisfy are then derived in terms of an extended set of partial differential equations. It is shown that affine transformations involving a scaling and a translation are scator holomorphic. These results are compared with holomorphy in quaternion and C 0,n Clifford algebras. Functions, such as the quadratic mapping, are shown not to satisfy the scator holomorphic conditions. KEYWORDS differential calculus, hypercomplex analysis, hyperholomorphic functions, scator algebra On sabbatical leave from Universidad Autónoma Metropolitana -Iztapalapa.