An electrophysiological study of the reinnervation of reimplanted and autotransplanted teeth in the cat

Robinson, P.P.

doi:10.1016/0003-9969(83)90172-3

Cited by 21 publications

(10 citation statements)

References 21 publications

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“…Several studies have reported that the reinnervation, tooth sensitivity restoration, and prognosis of the replanted teeth are favored if the tooth infection is controlled with an open apex and rapidly regained revascularization (40)(41)(42). In addition, nerve fibers are known to regenerate after the transection of the inferior alveolar nerve and to grow into the tooth pulp by the sprouting and ingrowth of intact nerves in adjacent tissues (43,44).…”

Section: Discussionmentioning

confidence: 98%

Histologic and Immunohistochemical Findings of a Human Immature Permanent Tooth with Apical Periodontitis after Regenerative Endodontic Treatment

Lei

Chen

Zhou

et al. 2015

Journal of Endodontics

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Section: Discussionmentioning

confidence: 98%

Histologic and Immunohistochemical Findings of a Human Immature Permanent Tooth with Apical Periodontitis after Regenerative Endodontic Treatment

Lei

Chen

Zhou

et al. 2015

Journal of Endodontics

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“…Electrical stimulation evoked a jaw-opening reflex nine to 24 weeks after surgery. Moreover, the reflex had a raised threshold and increased latency (Robinson 1983). On the other hand, histological analysis revealed that the quality of the nerve supply was not as good as in control teeth.…”

Section: Reinnervationmentioning

confidence: 89%

“…Therefore, atraumatic extraction of these teeth is difficult. In particular, the process of reinnervation was investigated in cats (Robinson 1983;Robinson 1987a, 1987b;Holland et al 1991).…”

Section: Catmentioning

confidence: 99%

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Tooth autotransplantations - lessons from animal models: a review

Langová¹,

Štembírek²,

Matalová³

et al. 2015

Vet. Med. - Czech

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Autotransplantation of teeth is the most natural technique to for replacing missing teeth in exposed parts of the dental arch. Reports from human patients indicate great progress toward successful transplantations. However, complications such as inflammation and ankylosis still occur. To understand regenerative processes after autotransplantations, several animal models have been used (monkeys, rodents, rabbits, cats and dogs) and histological/molecular methods have been established. This review aims to summarise knowledge from animal models and discuss their advantages or disadvantages with respect to possible usage in research.

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“…If these non-conducting collateral fibres do occur, then they are also unable to transport radiolabelled amino acids injected into the trigeminal ganglion; Byers & Matthews (1981) found no evidence of transmedian innervation of normal mandibular teeth using this method in the cat. In addition, Robinson (1983) has previously demonstrated collateral reinnervation of transplanted and reimplanted extracted teeth, in which all of the pre-existing nerve supply must have been disrupted.…”

Section: Discussionmentioning

confidence: 99%

Nerve growth factor depletion reduces collateral sprouting of cutaneous mechanoreceptive and tooth‐pulp axons in ferrets.

Doubleday¹,

Robinson²

1994

The Journal of Physiology

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1. Electrophysiological experiments were carried out to determine whether or not collateral sprouting of cutaneous low-threshold mechanoreceptive fibres could be detected and to investigate the effect of nerve growth factor (NGF) deprivation on the sprouting of these fibres and the fibres innervating tooth pulps. 2. In twenty-one ferrets (eleven of which had been autoimmunized against NGF) the right inferior alveolar nerve (IAN) was sectioned and prevented from regenerating. After 12 weeks, transmedian innervation from the left IAN was determined by stimulating the nerve whilst recording from electrodes implanted in the contralateral anterior teeth and also by single unit recordings from the nerve whilst mechanically and electrically stimulating the skin. The results were compared with those from ten control animals. 3. Transmedian innervation of contralateral teeth was found in none of the control animals; in all ten of the animals which had undergone denervation without immunization (4/10 canines, 17/20 incisors); but in only six of the eleven immunized and denervated animals (0/11 canines, 7/22 incisors). 4. Of 270 cutaneous mechanoreceptive units sampled in the controls, only four units had transmedian receptive fields, extending a maximum of 1 mm across the mid-line. After denervation, significantly more units (42 of 274) crossed the mid-line and extended up to 4 mm. After immunization and denervation only eleven of 305 units crossed the midline by a maximum of t mm.5. These data show that cutaneous low-threshold mechanoreceptive Af8 and Ad fibres, as well as Ad tooth pulp fibres, are able to undergo collateral sprouting. This sprouting is partially blocked by NGF depletion, suggesting that NGF plays an essential role in the process.

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An electrophysiological study of the reinnervation of reimplanted and autotransplanted teeth in the cat

Cited by 21 publications

References 21 publications

Histologic and Immunohistochemical Findings of a Human Immature Permanent Tooth with Apical Periodontitis after Regenerative Endodontic Treatment

Histologic and Immunohistochemical Findings of a Human Immature Permanent Tooth with Apical Periodontitis after Regenerative Endodontic Treatment

Tooth autotransplantations - lessons from animal models: a review

Nerve growth factor depletion reduces collateral sprouting of cutaneous mechanoreceptive and tooth‐pulp axons in ferrets.

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