An electrophoretic polymorphism in the serum transferrins of Praomys (Mastomys) natalensis

Abstract

Three serum transferrin phenotypes of Praomys (Mastomys) natalensis, and African rodent having a high incidence of many varieties of spontaneous neoplasms, were detected by electrophoresis and autoradiography. On electrophoresis, transferrin of Trf-K was found to be a protein that migrates slowly toward the cathode, whereas that of Trf-M migrates rapidly. Trf-KM is a heterozygous phenotype of the above two. Progeny testing demonstrated that these three serum transferrin phenotypes in Mastomys are probably controlled by two codominant allelic genes, Trfk and Trfm, at a single autosomal locus. The genotypes of these phenotypes may be Trfk/Trfk, Trfm/Trfm, and Trfk/Trfm.

An electrophoretic polymorphism in salivary amylases (Amy-1) of mastomys (Praomys coucha)

“…The second type was AMY-IB, a slow migrating one. Using mastomys (P. natalensis), three phenotypes of serum transferrin (Trf-K, Trf-M and Trf-KM) were detected (Ootsu et al, 1976). Kato (personal communication, 1989) Bender K, Adams M, Baverstock PR, et al (1984) Biochemicalmarkers in inbred strains of the rat (Rattus norvegicus).Immunogenetics 19, 257-266 Brdicka R (1973) Haemoglobin of mastomys natalensis (Rattus natalensis).…”

“…Polymorphism in the serum transferrins (Ootsu et al, 1976) and electrophoretic and chromatographic examinations of the native haemoglobin (Brdicka, 1973) have been reported in mastomys (Praeomys natalensis). Recently, Tanaka et 01.…”