This article presents an efficient S‐parameter extraction method for memristor‐based crossbar array circuits. The proposed approach involves converting the array into an equivalent circuit and analytically solving the circuit to obtain the S‐parameters. Memristor‐based crossbar array circuit simulations and corresponding experimental measurements are conducted to verify the high accuracy and low computation complexity of the established method. These numerical results indicate that the authors’ S‐parameter extraction method has the potential for evaluating signal integrity performance in neuromorphic chips, thus aiding their design and optimization for diverse applications.