An electrochemiluminescence aptasensor based on poly(aniline-luminol)/graphene oxide/chitosan for ultra-sensitive detection of Hg2+

Electrochemiluminescence Systems for Metal‐Ion Detection: A Systematic Review

“…Derivatives of luminol have been used in ECL systems for the detection of Hg(II) metal, such as N-(4-aminobutyl)N-ethylisoluminol (ABEI) [60] and Poly(anilineluminol). [61] The surface of poly(anilineluminol)/graphene oxide or P(ANi-Lu)/GO nanocomposites was modified using chitosan (CS) to obtain stable and good ECL properties. The aptamer was adsorbed on the surface of P(Ani-Lu)/GO/CS luminophore through electrostatic interaction, eventually forming a T-Hg-T configuration structure in the presence of Hg(II) in the ECL system.…”

“…[81,119] ITO/AuNPs electrode has many advantages, such as the interference to emit light from the sample matrix can be reduced, the ITO/ AuNPs electrode preserving good optical transparency with highly enhanced ECL activity, and the orientation of the oligonucleotides and steric space is more flexible than that on a flat electrode. [61] Hai et al developed a highly sensitive ECL with a "turn-on" aptamer sensor for the detection of lead(II) ions based on the formation of a G-quadruplex on a graphene/ AuNP-modified ITO electrode. [119] Moreover, Babamiri et al developed functionalized magnetic nanoparticles (MNPs) with good magnetic performance to enhance the electron transfer between the nanoprobe and the ITO electrode.…”

“…[111] The most developed co-reactants for Hg(II) detection were K 2 S 2 O 8 (potassium persulfate) [31,92,111,123,143,163,168,169] and TPrA (tripropylamine), [71,72,74,[79][80][81]96,97,167] although several studies have succeeded in developing ECL systems without co-reactants. [61,68] The developed ECL system provided satisfactory results when used to measure Hg(II) levels in various environmental samples.…”

“…Interestingly, Huang et al reported the utilization of poly aniline-luminol as a luminophore without co-reactant to detect Hg(II) levels at the TO electrode. [61] By adding aptamer adsorbed on the surface of luminophore, the low LOD value was obtained about 4.8×10 À 16 M in the measurement range of 10 À 15 -10 À 7 M. Moreover, various ECL systems have been successfully developed to detect Hg(II) ions.…”

Efficient sensitization of CdTe QDs towards PTCDA for sensitive photoelectrochemical Hg2+ assay

“…At present, numerous analytical techniques such as uorescence spectroscopy, colorimetry, electrochemistry, and electrochemiluminescence assays are adopted for the detection of trace amounts of Hg 2+ in the elds of environment, food, pharmaceuticals, and daily chemicals. [4][5][6][7] Nevertheless, these methods remain inefficient in terms of background signal, stability, and sensitivity. Photoelectrochemical (PEC) biosensing is an emerging and promising analytical method that combines the characteristics of optical analysis, electrochemical analysis, and biosensing technology.…”