An electrochemical sensor based on molecularly imprinted polydopamine coated on reduced graphene oxide for selective detection of ornidazole

Abstract

The electrochemical sensing of ornidazole (OR) was achieved with a highly selective sensor fabricated by a combination of an electrochemically reduced graphene oxide (ERGO) and molecularly imprinted polydopamine (PDA). The sensor (OR-imp@PDA/ERGO/GCE) was synthesized by electrochemical polymerization of dopamine (DA) on ERGO modified glassy carbon electrode (GCE). The analytical response of the sensor changed linearly with OR concentration varying from 1.5 × 10 À 9 M to 1.0 × 10 À 8 M and 1.0 × 10 À 8 M to 2.0 × 10 À 7 M, and the detection limit was defined as 1.1 × 10 À 9 M. The proposed sensor ensured the highly sensitive detection of OR concentration because of the advantages of ERGO and molecularly imprinted PDA.

A Wireless, CRISPR-Polymer Dot Electrochemical Sensor for the Diagnosis of Bacterial Pneumonia and Multi-Drug Resistance

“…Electrochemical sensors can provide a versatile diagnostic platform for various disease targets due to the high sensitivity and reliability . However, the previous methods have used materials with poor water solubility and limited modification capabilities. − Polymer dot nanoparticles (PDs) have been developed as an alternative to semiconductor quantum dots (SQDs) to overcome the toxicity associated with heavy metals . PDs exhibit excellent water solubility and electroconductivity, rendering them great advantages as sensing materials. − Moreover, PDs can be endowed with diverse functions via surface modification, such as stimuli responsiveness, adhesion to targets, or selective binding of analytes …”