An electrochemical immunosensing method based on silver nanoparticles

Hao, Nan; Li, Hui; Long, Yi‐Tao; Zhang, Lei; Zhao, Xi-Rui; Xu, Danke; Chen, Hong‐Yuan

doi:10.1016/j.jelechem.2011.01.029

Cited by 35 publications

(14 citation statements)

References 29 publications

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“…[104][105][106] Wei et al have recently utilised these substrates for the multiplexed detection of DNA using a molecular beacon-based system. [108][109][110] and fluorescence spectroscopy 111,112 have been developed for the specific detection of protein-protein interactions. However, as discussed previously, SERS has some advantages over these methods and the technique has therefore been extensively applied for the analysis of proteins, with detection at the single molecule level being achieved.…”

Section: Multiplex Detection Of Disease-related Dna Targetsmentioning

confidence: 99%

Multiplex in vitro detection using SERS

2016

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The ability to detect multiple disease-related targets from a single biological sample in a quick and reliable manner is of high importance in diagnosing and monitoring disease. The technique known as surface enhanced Raman scattering (SERS) has been developed for the simultaneous detection of multiple targets present in biological samples. Advances in the SERS method have allowed for the sensitive and specific detection of biologically relevant targets, such as DNA and proteins, which could be useful for the detection and control of disease. This review focuses on the strengths of SERS for the detection of target molecules from complex mixtures and the clinical relevance of recent work combining SERS with multiplexed detection of biological targets.

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Section: Multiplex Detection Of Disease-related Dna Targetsmentioning

confidence: 99%

Multiplex in vitro detection using SERS

2016

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“…Porter highlighted the fact that although the number of assays reported with gold nanoparticles is much higher than those with silver, it is the silver nanoparticles that exhibit the better electrochemical properties [103] . Chen has developed the most sensitive electrochemical immunosensing method with a dynamic concentration range of 1-1000 ng/mL and a detection limit of 0.4 ng/mL [104] . The anti-microbial properties of silver are well documented [105] , and the antimicrobial activity of silver nanoparticles dominates research in this area [106] .…”

Section: Goldmentioning

confidence: 99%

Molecular recognition by gold, silver and copper nanoparticles

Tauran¹,

Brioude²,

Coleman³

et al. 2013

WJBC

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The intrinsic physical properties of the noble metal nanoparticles, which are highly sensitive to the nature of their local molecular environment, make such systems ideal for the detection of molecular recognition events. The current review describes the state of the art concerning molecular recognition of Noble metal nanoparticles. In the first part the preparation of such nanoparticles is discussed along with methods of capping and stabilization. A brief discussion of the three common methods of functionalization: Electrostatic adsorption; Chemisorption; Affinity-based coordination is given. In the second section a discussion of the optical and electrical properties of nanoparticles is given to aid the reader in understanding the use of such properties in molecular recognition. In the main section the various types of capping agents for molecular recognition; nucleic acid coatings, protein coatings and molecules from the family of supramolecular chemistry are described along with their numerous applications. Emphasis for the nucleic acids is on complementary oligonucleotide and aptamer recognition. For the proteins the recognition properties of antibodies form the core of the section. With respect to the supramolecular systems the cyclodextrins, calix[n]arenes, dendrimers, crown ethers and the cucurbitales are treated in depth. Finally a short section deals with the possible toxicity of the nanoparticles, a concern in public health.

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“…This method leads to the preconcentration of the metal component on the electrode surface and is usually more sensitive than the direct stripping method. It has been successfully employed in biosensing devices using SPEs [62,63]. An interesting approach was reported using a dual screen-printed working electrode device [64].…”

Section: Strategies For Electrochemical Detection Of Nanoparticlesmentioning

confidence: 99%

Electrochemical Detection and Characterization of Nanoparticles with Printed Devices

Martín‐Yerga

2019

Biosensors

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Innovative methods to achieve the user-friendly, quick, and highly sensitive detection of nanomaterials are urgently needed. Nanomaterials have increased importance in commercial products, and there are concerns about the potential risk that they entail for the environment. In addition, detection of nanomaterials can be a highly valuable tool in many applications, such as biosensing. Electrochemical methods using disposable, low-cost, printed electrodes provide excellent analytical performance for the detection of a wide set of nanomaterials. In this review, the foundations and latest advances of several electrochemical strategies for the detection of nanoparticles using cost-effective printed devices are introduced. These strategies will equip the experimentalist with an extensive toolbox for the detection of nanoparticles of different chemical nature and possible applications ranging from quality control to environmental analysis and biosensing.

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An electrochemical immunosensing method based on silver nanoparticles

Cited by 35 publications

References 29 publications

Multiplex in vitro detection using SERS

Multiplex in vitro detection using SERS

Molecular recognition by gold, silver and copper nanoparticles

Electrochemical Detection and Characterization of Nanoparticles with Printed Devices

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