An efficient synthesis of mono-, di-, and tri-substituted 1,3-thiazoles employing functionalized thioamides as thiocarbonyl precursors

Abstract

Herein, we report an efficient strategies to synthesize functionalized 1,3-thiazoles using alkyl 2-amino-2-thioxoacetates. The synthetic precursor thioamides react effortlessly with electrophilic reagents and transformed into a series of phenyl-, methyl-,...