An efficient resin for solid-phase extraction and determination by UPLCMS/MS of 44 pharmaceutical personal care products in environmental waters

Zhu, Feng; Yao, Zhijian; Ji, Wenliang; Liu, Deye; Zhang, Hao; Li, Aimin; Huo, Zongli; Zhou, Qing

doi:10.1007/s11783-020-1228-y

Cited by 12 publications

(3 citation statements)

References 30 publications

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“…Different studies applied attractive modifications to these traditional cartridges, to obtain the best recoveries for a large spectrum of compounds. Zhu et al [52] developed, characterized and tested a hydrophilic resin based on poly(N-vinyl pyrrolidone-co-divinylbenzene) (NVP-co-DVB) that improved the average absolute recovery for 44 PPCPs, with respect to the use of HLB sorbents. Alternatively, Caban et al [62] studied the modification of the columns through the application of additional sorbents on top of a polymeric HLB column to improve the SPE of 15 analytes (pharmaceuticals and estrogens) from water.…”

Section: Sorbents and Formatsmentioning

confidence: 99%

Sample Preparation to Determine Pharmaceutical and Personal Care Products in an All-Water Matrix: Solid Phase Extraction

Sadutto

Picó

2020

Molecules

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Pharmaceuticals and personal care products (PPCPs) are abundantly used by people, and some of them are excreted unaltered or as metabolites through urine, with the sewage being the most important source to their release to the environment. These compounds are in almost all types of water (wastewater, surface water, groundwater, etc.) at concentrations ranging from ng/L to µg/L. The isolation and concentration of the PPCPs from water achieves the appropriate sensitivity. This step is mostly based on solid-phase extraction (SPE) but also includes other approaches (dispersive liquid-liquid microextraction (DLLME), buckypaper, SPE using multicartridges, etc.). In this review article, we aim to discuss the procedures employed to extract PPCPs from any type of water sample prior to their determination via an instrumental analytical technique. Furthermore, we put forward not only the merits of the different methods available but also a number of inconsistencies, divergences, weaknesses and disadvantages of the procedures found in literature, as well as the systems proposed to overcome them and to improve the methodology. Environmental applications of the developed techniques are also discussed. The pressing need for new analytical innovations, emerging trends and future prospects was also considered.

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Section: Sorbents and Formatsmentioning

confidence: 99%

Sample Preparation to Determine Pharmaceutical and Personal Care Products in an All-Water Matrix: Solid Phase Extraction

Sadutto

Picó

2020

Molecules

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“…However, besides the pH effect, it was found that the NOM between (6-18) kDa exhibited higher impacts on the adsorption at neutral and high pHs, as the influence of NOM between (6-18) kDa and (18-60) kDa became more evident at pH 3 (the adsorbed concentration was dropped by 66% and 86%, respectively). Using an equation of R min = (3V/4) 1/3 (where R min and V represent the size in nm and MW in Da, respectively) for the NOM size prediction [41], the size ranges of NOM between (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18) kDa and (18-60) kDa were (1.2-1.7) and (1.7-2.6) nm, respectively. Our BET analysis indicated that ~90% of the pore sizes of GO-Fe 3 O 4 -2.5 ranged from 1 to 7 nm (Figure 3A).…”

Section: Selective Adsorption By Pore Size Tuning: Isothermmentioning

confidence: 99%

“…Over 80% of the intake dose can be excreted from the human body after metabolism [ 15 ]. As a result, PRO is frequently detected in rivers [ 16 , 17 ] and estuaries [ 18 ] in concentrations of up to 142 ng/L.…”

Section: Introductionmentioning

confidence: 99%

The Influences of Pore Blockage by Natural Organic Matter and Pore Dimension Tuning on Pharmaceutical Adsorption onto GO-Fe3O4

Lin

Huang

et al. 2023

Nanomaterials

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The ubiquitous presence of pharmaceutical pollution in the environment and its adverse impacts on public health and aquatic ecosystems have recently attracted increasing attention. Graphene oxide coated with magnetite (GO-Fe3O4) is effective at removing pharmaceuticals in water by adsorption. However, the myriad compositions in real water are known to adversely impact the adsorption performance. One objective of this study was to investigate the influence of pore blockage by natural organic matter (NOM) with different sizes on pharmaceutical adsorption onto GO-Fe3O4. Meanwhile, the feasibility of pore dimension tuning of GO-Fe3O4 for selective adsorption of pharmaceuticals with different structural characteristics was explored. It was shown in the batch experiments that the adsorbed pharmaceutical concentrations onto GO-Fe3O4 were significantly affected (dropped by 2–86%) by NOM that had size ranges similar to the pore dimensions of GO-Fe3O4, as the impact was enhanced when the adsorption occurred at acidic pHs (e.g., pH 3). Specific surface areas, zeta potentials, pore volumes, and pore-size distributions of GO-Fe3O4 were influenced by the Fe content forming different-sized Fe3O4 between GO layers. Low Fe contents in GO-Fe3O4 increased the formation of nano-sized pores (2.0–12.5 nm) that were efficient in the adsorption of pharmaceuticals with low molecular weights (e.g., 129 kDa) or planar structures via size discrimination or inter-planar π-π interaction, respectively. As excess larger-sized pores (e.g., >50 nm) were formed on the surface of GO-Fe3O4 due to higher Fe contents, pharmaceuticals with larger molecular weights (e.g., 296 kDa) or those removed by electrostatic attraction between the adsorbate and adsorbent dominated on the GO-Fe3O4 surface. Given these observations, the surface characteristics of GO-Fe3O4 were alterable to selectively remove different pharmaceuticals in water by adsorption, and the critical factors determining the adsorption performance were discussed. These findings provide useful views on the feasibility of treating pharmaceutical wastewater, recycling valuable pharmaceuticals, or removing those with risks to public health and ecosystems.

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Photocatalytic degradation of the acetaminophen by nanocrystal-engineered TiO2 thin film in batch and continuous system

Katal

Tanhaei

2020

Front. Environ. Sci. Eng.

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An efficient resin for solid-phase extraction and determination by UPLCMS/MS of 44 pharmaceutical personal care products in environmental waters

Cited by 12 publications

References 30 publications

Sample Preparation to Determine Pharmaceutical and Personal Care Products in an All-Water Matrix: Solid Phase Extraction

Sample Preparation to Determine Pharmaceutical and Personal Care Products in an All-Water Matrix: Solid Phase Extraction

The Influences of Pore Blockage by Natural Organic Matter and Pore Dimension Tuning on Pharmaceutical Adsorption onto GO-Fe3O4

Photocatalytic degradation of the acetaminophen by nanocrystal-engineered TiO2 thin film in batch and continuous system

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