“…IR (neat): 2959 (C-H), 1731 (C=O), 1222 (C-O and C-N), 1024 (C-O) cm -1 .1 H NMR (400 MHz, CDCl 3 ): diast1 = 7.26 (d, J = 1.9 Hz, 2 H),6.94 (td, J = 8.6, 4.9 Hz, 2 H), 4.24-4.11 (m, 2 H), 4.09-3.79 (m, 4 H), 3.76-3.69 (m, 6 H), 3.58-3.39 (m, 1 H), 2.78-2.54 (m, 2 H), 2.50 (s, 3 H), 1.25 (t, J = 7.1 Hz, 3 H).31 P NMR (162 MHz, CDCl 3 ): diast1 = 22.8.19 F NMR (377 MHz, CDCl 3 ): diast1 = -113.9.13 C NMR (100 MHz, CDCl 3 ): diast1 = 172.0, 162.4 (d, J = 246.5 Hz), 133.6, 129.4 (d, J = 8.1 Hz, 2 C), 115.5 (d, J = 21.4, 2 C), 84.0, 75.1 (d, J = 10.0 Hz), 72.4, 65.4, 61.6, 52.9 (dd, J = 6.5, 2.9 Hz, 2 C), 45.0, 42.8, 14.1.1 H NMR (400 MHz, CDCl 3 ): diast2 = 7.26 (d, J = 1.9 Hz, 2 H), 6.94 (td, J = 8.6, 4.9 Hz, 2 H), 4.24-4.11 (m, 2 H), 4.09-3.79 (m, 4 H), 3.76-3.69 (m, 6 H), 3.58-3.39 (m, 1 H), 2.78-2.54 (m, 2 H), 2.54 (s, 3 H), 1.25 (t, J = 7.1 Hz, 3 H).31 P NMR (162 MHz, CDCl 3 ): diast2 = 23.1.19 F NMR (377 MHz, CDCl 3 ): diast2 = -114.1.13 C NMR (100 MHz, CDCl 3 ): diast2 = 170.9, 162.4 (d, J = 246.5 Hz), 133.2 (d, J = 3.1 Hz), 129.1 (d, J = 8.0 Hz, 2 C), 115.5 (d, J = 21.4 Hz, 2 C), 83.9, 75.6 (d, J = 9.8 Hz), 71.5, 65.2 (d, J = 164.5 Hz), 61.6, 52.9 (d, J = 6.4 Hz, 2 C), 45.8, 43.0, 14.0. HRMS (ESI + ): m/z [M + H] + calcd for C 17 H 26 FNO 7 P: 406.1431; found: 406.1420.Ethyl 5-(((Diethoxyphosphoryl)methoxy)methyl)-2-methyl-3-(4-(trifluoromethyl)phenyl)isoxazolidine-5-carboxylate (7g)By following general procedure 3, using diethyl [(allyloxy)methyl]phosphonate 1a (0.70 mmol, 0.20 g) and nitrone 6d (0.70 mmol, 0.14 g), a mixture of two inseparable diastereoisomers 7g was obtained.Yield: 0.23 g (69%); viscous oil; R f = 0.54 (EtOAc).IR (neat): 2984 (C-H), 1734 (C=O), 1254 (C-O and C-N), 1019 (C-O) cm -1 .…”