An efficient and practical approach for the continuous‐flow synthesis of 5‐hydroxymethylfurfural from carbohydrates using an acidic ionic liquid
Tan Van Nguyen,
Trinh Hao Nguyen,
Ha Bich Phan
et al.
Abstract:BACKGROUNDFlow chemistry is becoming an essential technique in organic synthesis. This trend is expected to continue and broaden in scope and complexity. This miniaturized protocol that includes microreactors enables excellent heat transfer, low solvent wastage, shorter reaction times, higher productivity, and higher space‐time yields.RESULTSIn this study, we synthesized four ionic liquids and applied them as catalysts for the selective preparation of 5‐HMF from fructose using the continuous flow system. The e… Show more
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