“…Besides the non-overlap of the three-dimensional boxes, the constraints that have been usually considered are the vertical stability of the cargo and the multi-drop situations (also known as LIFO constraints), although other constraints may also appear, such as the load bearing strength of the boxes, time windows and pickups and deliveries. The approaches used to solve the problem have been mainly heuristic (Bortfeldt, 2012;Bortfeldt & Homberger, 2013;Ceschia, Schaerf, & Stützle 2013;Fuellerer, Doerner, Hartl, & Iori, 2010;Gendreau, Iori, Laporte, & Martello, 2006;Lacomme, Toussaint, & Duhamel, 2013;Moura & Oliveira, 2009;Ruan, Zhang, Miao, & Shen, 2013;Tao & Wang, 2013;Tarantilis, Zachariadis, & Kiranoudis, 2009;Zachariadis, Tarantilis, & Kiranoudis, 2012Zhu, Qin, Lim, & Wang, 2012). The integrated problem is usually hierarchically decomposed, where the vehicle routing is solved at the higher level and the container loading at the lower level.…”