An economic compact high voltage pulse generator

Novac, B.M.; Smith, I.R.; Goh, S.E.

doi:10.1049/ic:20000275

Cited by 3 publications

(2 citation statements)

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“…It consists of a DC supply, an IGBT (MOSFET can also be used), two coupled inductors, a high voltage diode, a capacitor, and a spark gap. Similar work can be found in Novac, 29 which uses an exploding foil instead of an IGBT. This makes the system more powerful but not repetitive, contrary to our design.…”

Section: Structure Of the Generatormentioning

confidence: 79%

Compact low‐cost high‐voltage pulse generator for biological applications

Achour

Starzyński

Kasprzycka

et al. 2019

Circuit Theory & Apps

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In order to test the electroporation applied to mammalian cells (DU-145 human prostate cancer cell line), treated with short (30 ns) intense electric pulses, a new architecture of a pulse generator is proposed. It provides a quasirectangular output with nanosecond rise time and fully controlled repetition rate, which allows the control of the electric field dose applied to the cells.The system consists of a pulse generator with a high voltage gain and power efficiency, but it outputs exponential pulses. To improve that side, a pulse forming line (PFL) is used to get the final rectangular pulse. The whole device is designed using a multilayer printed circuit board (PCB) technology. That reduces the cost and increases the compactness of the generator. The output is connected to a special electroporation cuvette filled with special liquid. The impedance of such load is not well known, that is why some preliminary tests were carried out to identify the load of the generator. A number of simulations allowed to validate the design and to find out the influence of different parameters on its characteristics. Finally, a compact 4-kV generator was built and tested. The results are discussed and compared with those obtained from simulations.

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Section: Structure Of the Generatormentioning

confidence: 79%

Compact low‐cost high‐voltage pulse generator for biological applications

Achour

Starzyński

Kasprzycka

et al. 2019

Circuit Theory & Apps

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“…Voltage pulses in excess of 250 kV have been generated on many occasions, with a fuse package containing only one fuse [3], and without any apparent damage.…”

Section: High-voltage Transformermentioning

confidence: 99%

Multiple-pulse, twin-output, high-voltage generator

Novac

Smith

Gregory

2000

J. Phys. D: Appl. Phys.

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This paper describes the development of a compact, proof-of-principle generator for the production of two synchronized series of high-voltage pulses from the single discharge of a capacitor. The pulses are produced by an array of parallel-connected exploding fuses, with compact transformers enabling the required level of output voltage to be obtained. Experimental results are presented and compared with theoretical predictions.

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