An economic analysis of premarriage prevention of hepatitis B transmission in Iran

Adibi, Peyman; Rezailashkajani, Mohammadreza; Roshandel, Delnaz; Behrouz, Negar; Ansari, Shahin; Somi, Mohammad Hossein; Shahraz, Saeed; Zali, Mohammad Reza

doi:10.1186/1471-2334-4-31

Cited by 23 publications

(33 citation statements)

References 14 publications

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“…Approximately 1.8 billion people have serological evidence of hepatitis B virus (HBV) infection with 350 million estimated to have chronic infection; at least 500 000 of these patients die from liver malignancy and cirrhosis 2. The WHO estimates that 170 million individuals worldwide have the hepatitis C virus (HCV) 3.…”

mentioning

confidence: 99%

Is there a need to include HIV, HBV and HCV viruses in the Saudi premarital screening program on the basis of their prevalence and transmission risk factors?

Alswaidi

O’Brien

2009

Journal of Epidemiology & Community Health

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The prevalences of HIV, HBV and HCV in Saudi Arabia are among the lowest worldwide. However, all the important risk factors associated with transmitting these viruses are significantly present in the Saudi community. Saudi Arabia is financially capable of screening for these infections in the mandatory premarital program and of providing medical care for the discovered cases, but focusing on the health education programs may offset the need to mandatory testing.

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mentioning

confidence: 99%

Is there a need to include HIV, HBV and HCV viruses in the Saudi premarital screening program on the basis of their prevalence and transmission risk factors?

Alswaidi

O’Brien

2009

Journal of Epidemiology & Community Health

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“…Data related to cost of vaccination and screening are gathered from GAVI and United Nations (UN) reports as well as economic evaluation studies conducted in Thailand, and Iran [34–37]. Assuming that organizing and delivering process of new vaccination plans would be implemented via the established healthcare delivery system [9], we did not include additional capital costs of expanding vaccination schemes, i.e.…”

Section: Methodsmentioning

confidence: 99%

Cost-Effectiveness Analysis of Hepatitis B Vaccination Strategies to Prevent Perinatal Transmission in North Korea: Selective Vaccination vs. Universal Vaccination

Lee

Park

2016

PLoS ONE

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BackgroundTo tackle the high prevalence of Hepatitis B virus (HBV) infection in North Korea, it is essential that birth doses of HBV vaccines should be administered within 24 hours of birth. As the country fails to provide a Timely Birth Dose (TBD) of HBV vaccine, the efforts of reducing the high prevalence of HBV have been significantly hampered.MethodsTo examine the cost-effectiveness of vaccination strategies to prevent perinatal transmission of HBV in North Korea, we established a decision tree with a Markov model consisting of selective, universal, and the country’s current vaccination program against HBV. The cost-effectiveness analysis was performed from societal and payer’s perspectives and evaluated by Disability Adjusted Life Year (DALY).ResultsThe results suggest that introducing the universal vaccination would prevent 1,866 cases of perinatal infections per 100,000 of the birth cohort of 2013. Furthermore, 900 cases of perinatal infections per 100,000 could be additionally averted if switching to the selective vaccination. The current vaccination is a dominated strategy both from the societal and payer’s perspective. The Incremental Cost-Effectiveness Ratio (ICER) between universal and selective vaccination is $267 from the societal perspective and is reported as $273 from the payer’s perspective.ConclusionBased on the assumption that the 2012 Gross Domestic Product (GDP) per capita in North Korea, $582.6 was set for cost-effectiveness criteria, the result of this study indicates that selective vaccination may be a highly cost-effective strategy compared to universal vaccination.

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“…CEA (cost-effectiveness analysis) was performed in 9 economic evaluation studies. 36,[38][39][40]43,44,47,50,53 2. CBA (cost-benefit analysis) was evaluated by 5 studies.…”

Section: Identification Of Relevant Researchmentioning

confidence: 99%

Economic evaluation of HBV vaccination: A systematic review of recent publications (2000–2013)

Torre

Mannocci

Saulle

et al. 2016

Human Vaccines & Immunotherapeutics

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Aim: To conduct a systematic review of the economic evaluations (EE) of HBV vaccination, taking also into account the studies published in the new millennium. Methods: An extensive scientific literature review was conducted using two electronic medical journal databases: Scopus and PubMed engines for published studies on EE of HBV vaccination. Results: 22 articles were reviewed, 9, 5 and 8 cost-effectiveness, cost-benefit and cost-utility analysis, respectively. Studies were mainly concerning EE of universal vaccination (UV), mostly with regards to low or low-medium income countries. For high income countries, EE were focused on the possible implementation of HBV vaccination in particular settings, such as diabetic, renal and other chronic conditions care, as well as infectious diseasesUV has usually a very good cost-effectiveness ratio (80%), ranging from cost-saving (China) or few Euro per LY/QALY gained (in Thailand, and Vietnam) to 630.00$/ QALY in USA (Asian and Pacific Islands) Moreover, EE of HBV vaccination are favorable in the infectious diseases field as well as for chronic conditions. In relation to diabetes the studies gave controversial results. Conclusion: This systematic review highlighted the importance of introducing HBV vaccination not only for infant UV program but also for other settings in which patients are people affected by communicable and non-communicable diseases.

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An economic analysis of premarriage prevention of hepatitis B transmission in Iran

Abstract: Background: To assess the economic aspects of HBV (hepatitis B virus) transmission prevention for premarriage individuals in a country with cultural backgrounds like Iran and intermediate endemicity of HBV infection.

Cited by 23 publications

References 14 publications

Is there a need to include HIV, HBV and HCV viruses in the Saudi premarital screening program on the basis of their prevalence and transmission risk factors?

Is there a need to include HIV, HBV and HCV viruses in the Saudi premarital screening program on the basis of their prevalence and transmission risk factors?

Cost-Effectiveness Analysis of Hepatitis B Vaccination Strategies to Prevent Perinatal Transmission in North Korea: Selective Vaccination vs. Universal Vaccination

Economic evaluation of HBV vaccination: A systematic review of recent publications (2000–2013)

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