An echocardiographic study of patients with cardiovascular disease during dental treatment using local anesthesia

Hirota, Yuki; Sugiyama, Katsumi; Joh, Shigeharu; Kiyomitsu, Y

doi:10.1016/0278-2391(86)90193-x

Cited by 19 publications

(10 citation statements)

References 10 publications

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“…In contrast to our results, Hirota et al 34 reported that greater hemodynamic changes were observed in class III patients than in patients in other groups. However, their subjects were so few (n = 2) that their findings were unreliable.…”

Section: Discussioncontrasting

confidence: 99%

Cardiovascular response to epinephrine-containing local anesthesia in patients with cardiovascular disease

Niwa¹,

Sugimura²,

Satoh³

et al. 2001

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, an

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Section: Discussioncontrasting

confidence: 99%

Cardiovascular response to epinephrine-containing local anesthesia in patients with cardiovascular disease

Niwa¹,

Sugimura²,

Satoh³

et al. 2001

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, an

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“…Our results are in accordance with those of several authors who demonstrated that the effects of felypressin on the cardiovascular system are much smaller than the effects of catecholamines [1,6,7]. Gerke et al [5] reported potentiation of the vasoconstrictor effects of epinephrine by felypressin on the central artery of the rabbit's ear, but in the present study the opposite effect was found on the arterial blood pressure of rats: the combination reduced the vasoconstrictor effect of epinephrine, causing a smaller elevation of the MAP.…”

supporting

confidence: 96%

Hemodynamic effects of felypressin and epinephrine on anesthetized rats

Singi

OLIVEIRA

Araujo

et al. 2003

Journal of Anesthesia

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Rats (n ϭ 10) were used. The animals were anesthetized with sodium pentobarbital (30 mg·kg Ϫ1 ) intraperitoneally. After tracheotomy, cannulation of the jugular vein and the carotid artery was performed for injection of drugs and to record the mean arterial blood pressure (MAP), respectively. Preliminary studies were done to determine the doses. The injected doses were: 27.29µM of epinephrine, 4.80 µM of felypressin, and a combination of 27.29 µM of epinephrine plus 4.80 µM of felypressin. The substances were prepared with serum. Epinephrine and felypressin were administered by i.v. injection of 0.2 ml, and the combination by i.v. injection of 0.4 ml, both followed by injection of 0.2 ml of serum to flush the residual. The interval between administrations was 15 min, and the rate of administration was 0.2 ml per 5 s. The hemodynamic variables stabilized, on average, 15 min after the end of the preparation. The sequence of application of the doses was drafted before each experiment. MAP was recorded with a transducer TBS 104A, coupled to a BIOPAC SYSTEM Model MP100 (Santa Barbara, CA, USA). An electrocardiograph ECG-4-FUNBEC (São Paulo, Brazil) was used to record the heart rate (HR). The electrocardiogram was evaluated in D2 derivation (with the negative electrode on the right front leg and the positive electrode on the left rear leg). The records were made before and 15 s after administration of the substances, at the time of the highest effect. The results were analyzed by ANOVA (Student-Newman-Keuls), with P Ͻ 0.05 indicating statistical significance.

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“…Different types of anesthesia have been reported to cause hemodynamic changes during induction and maintenance of anesthesia [3][4][5][6]. Preference for any one for the anesthetic techniques is a subject of investigation.…”

mentioning

confidence: 99%