An easy schedule for postsurgical radioiodine administration in newly diagnosed differentiated thyroid carcinoma patients

Lupoli, Gelsy Arianna; Poggiano, Maria Rita; Panico, Annalisa; Granieri, Luciana; Lupoli, Roberta; Cacciapuoti, Marianna; Lupoli, Giovanni

doi:10.1111/cen.12004

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“…For these thyroidectomized patients with L-T4 replacement therapy, L-T4 withdrawal prior to 131 I administration is used to obtain increased TSH levels for improving the sensitivity of thyroglobulin (Tg) monitoring and stimulating sufficient radioiodine uptake for diagnostic imaging or ablation therapy [2]. The optimal TSH concentration is unknown, but a level of 30 mIU/l or over has been deemed sufficient for both imaging and treatment purposes [3].…”

Section: Introductionmentioning

confidence: 99%

Discriminant function analysis of the occurrence risk of abnormal electrocardiogram in thyroidectomized differentiated thyroid carcinoma patients with short-term overt hypothyroidism

et al. 2015

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The thyroidectomized DTC patients undergoing short-term L-T4 withdrawal before their first radioiodine ablative therapy, who had one or more of the above-mentioned risk factors, are likely to show abnormal ECG findings. The formulas from discriminant function analysis may be helpful for predicting patients with abnormal ECG with short-term L-T4 withdrawal and allow appropriate medical intervention beforehand.

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Section: Introductionmentioning

confidence: 99%