An Early Clinical Evaluation of Clopenthixol in Treatment-Resistant Female Schizophrenic Patients

Wolpert, Arthur; Sheppard, Charles; Merlis, Sidney

doi:10.1176/ajp.124.5.702

Cited by 4 publications

(2 citation statements)

References 2 publications

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“…Clopentixol, the thioxanthene analogue of perphenazine, was introduced in the early 1960s, with the literature repeating an established pattern -therapeutic benefit in chronic schizophrenia unresponsive to other medications (Ban 1963;Wolpert 1967). As with flupentixol, it was originally presented as a racemic mix which, like flupentixol, has a striking impact on its pharmacology (Johnstone 1978).…”

Section: Zuclopenthixol (Zuclopentixol) (Table 1)mentioning

confidence: 99%

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Meet the relatives: a reintroduction to the clinical pharmacology of ‘typical’ antipsychotics (Part 2)

Owens

2012

Adv. psychiatr. treat

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SummaryThis second of two articles on the ‘typical’ (‘first-generation’) antipsychotics covers non-phenothiazines: thioxanthenes (flupentixol and zuclopenthixol), butyrophenones/diphenylbutylpiperidines (including one-time world market-leader haloperidol, and pimozide) and sulpiride, for many years the only substituted benzamide available in the UK. Several tolerability issues ascribed specifically or more frequently to older antipsychotics are also discussed.

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Section: Zuclopenthixol (Zuclopentixol) (Table 1)mentioning

confidence: 99%

“…Some early trials utilised restraint in dosage (e.g. Wolpert 1967: 50 mg/day), but most studies on which equivalence tables are based used much higher doses (e.g. Serafetinides 1972: average 227 mg/day).…”

Section: Zuclopenthixol (Zuclopentixol) (Table 1)mentioning

confidence: 99%

Meet the relatives: a reintroduction to the clinical pharmacology of ‘typical’ antipsychotics (Part 2)

Owens

2012

Adv. psychiatr. treat

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The neuroleptically active isomer of clopenthixol. A presentation of five double-blind clinical investigations and other studies with cis(Z)-clopenthixol (Cisordinol�, Clopixol�)

Gravem¹,

Elgen²

1981

Acta Psychiatr Scand

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Cis(Z)‐Clopenthixol The Neuroleptically Active Isomer of Clopenthixol. A presentation of five double‐blind clinical investigations and other studies with cis(Z)‐clopenthixol (Cisordinol®, Clopixol®)

Gravem¹,

Elgen²

1981

Acta Psychiatr Scand

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An Early Clinical Evaluation of Clopenthixol in Treatment-Resistant Female Schizophrenic Patients

Cited by 4 publications

References 2 publications

Meet the relatives: a reintroduction to the clinical pharmacology of ‘typical’ antipsychotics (Part 2)

Meet the relatives: a reintroduction to the clinical pharmacology of ‘typical’ antipsychotics (Part 2)

The neuroleptically active isomer of clopenthixol. A presentation of five double-blind clinical investigations and other studies with cis(Z)-clopenthixol (Cisordinol�, Clopixol�)

Cis(Z)‐Clopenthixol The Neuroleptically Active Isomer of Clopenthixol. A presentation of five double‐blind clinical investigations and other studies with cis(Z)‐clopenthixol (Cisordinol®, Clopixol®)

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