An axonemal intron splicing program sustains Plasmodium male development
Jiepeng Guan,
Peijia Wu,
Xiaoli Mo
et al.
Abstract:Differentiation of male gametocytes into flagellated fertile male gametes relies on the assembly of axoneme, a major component of male development for mosquito transmission of the malaria parasite. RNA-binding protein (RBP)-mediated post-transcriptional regulation of mRNA plays important roles in eukaryotic sexual development, including the development of female Plasmodium. However, the role of RBP in defining the Plasmodium male transcriptome and its function in male gametogenesis remains incompletely underst… Show more
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