An Autopsy Case of &lt;b&gt;&lt;i&gt;Edwardsiella tarda&lt;/i&gt;&lt;/b&gt; Meningoencephalitis

Makino, Takahiro; Sugano, Isamu; Kamitsukasa, Ikuo

doi:10.1159/000492488

Cited by 2 publications

(4 citation statements)

References 8 publications

(14 reference statements)

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“…Generally, enteritis caused by E. tarda often resolves spontaneously with symptomatic treatment and is rarely clinically severe. However, intra-abdominal abscess, cholecystitis, cholangitis, cellulitis, necrotizing fasciitis, meningitis, and osteomyelitis have been reported as extraintestinal infections, although the number of reports is small [ 9 – 11 , 14 – 18 ]. Meanwhile, bacteremia is rare, occurring in less than 5% of all cases of E. tarda infections [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

Acute cholecystitis with sepsis due to Edwardsiella tarda: a case report

Hara,

Tanaka,

Nishiwada

et al. 2023

surg case rep

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Background Edwardsiella tarda (E. tarda) is a Gram-negative facultative anaerobe belonging to Enterobacteriales and is commonly isolated from fishes and reptiles. Infection due to E. tarda is uncommon among humans, with a reported human retention rate of 0.001%. It can cause sepsis in the elderly or those with pre-existing conditions such as liver failure, autoimmune disease, or malignancy. E. tarda is susceptible to many antibiotics; however, a high mortality rate (approximately 40%) has been reported with sepsis. Case presentation A 65-year-old woman presented to our hospital with a chief complaint of fever and abdominal pain for 2 days. Her blood tests showed elevated inflammatory markers, and contrast-enhanced computed tomography showed distention and wall thickening of the gallbladder and inflammation of peri-gallbladder fat. Subsequently, a diagnosis of cholecystitis with systemic inflammatory response syndrome was made. Laparoscopic cholecystectomy was performed after starting antimicrobial therapy. Blood culture of samples obtained on admission were positive for E. tarda, which was also detected in bile juice culture. Therefore, she was diagnosed with bacteremia caused by E. tarda, and postoperative antimicrobial therapy was continued. The patient improved, and there were no complications. Conclusions We experienced an extremely rare case of acute cholecystitis caused by E. tarda. Only a few cases of acute cholecystitis due to E. tarda have been reported. Furthermore, similar to this case, no previous study has reported the detection of E. tarda in both blood and bile cultures in acute cholecystitis cases. In addition to appropriate surgical intervention, continuous administration of antibiotics based on culture results resulted in a favorable outcome.

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Section: Discussionmentioning

confidence: 99%

Acute cholecystitis with sepsis due to Edwardsiella tarda: a case report

Hara,

Tanaka,

Nishiwada

et al. 2023

surg case rep

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“…Since that report, only a handful of CNS cases have been published over the intervening 50+ years. These CNS cases include subdural hematoma [164], neonatal brain abscesses [165], meningoencephalitis [166], and the most common E. tarda neurologic complication, meningitis.…”

Section: Cns Illnessesmentioning

confidence: 99%

“…There have been seven published cases of E. tarda meningitis including one case of meningoencephalitis [13,[166][167][168]. Four cases occurred in adults and three in neonates.…”

Section: Cns Illnessesmentioning

confidence: 99%

“…Four cases occurred in adults and three in neonates. Adult cases (17 to 78 years) have presented in persons with fever, headache, and altered mental status who are either compromised because of steroid therapy systemic lupus erythematosus [8] or have other predisposing conditions to infection such as cirrhosis due to excessive ethanol abuse or eating raw fish [166]. In contrast, neonates suffer from prematurity (33-35 weeks), low birth weight, and failure to thrive [8,168].…”

Section: Cns Illnessesmentioning

confidence: 99%

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Expanding the Spectrum of Diseases and Disease Associations Caused by Edwardsiella tarda and Related Species

Janda,

Duman

2024

Microorganisms

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The genus Edwardsiella, previously residing in the family Enterobacteriaceae and now a member of the family Hafniaceae, is currently composed of five species, although the taxonomy of this genus is still unsettled. The genus can primarily be divided into two pathogenic groups: E. tarda strains are responsible for almost all human infections, and two other species (E. ictaluri, E. piscicida) cause diseases in fish. Human infections predominate in subtropical habitats of the world and in specific geospatial regions with gastrointestinal disease, bloodborne infections, and wound infections, the most common clinical presentations in decreasing order. Gastroenteritis can present in many different forms and mimic other intestinal disturbances. Chronic gastroenteritis is not uncommon. Septicemia is primarily found in persons with comorbid conditions including malignancies and liver disease. Mortality rates range from 9% to 28%. Most human infections are linked to one of several risk factors associated with freshwater or marine environments such as seafood consumption. In contrast, edwardsiellosis in fish is caused by two other species, in particular E. ictaluri. Both E. ictaluri and E. piscicida can cause massive outbreaks of disease in aquaculture systems worldwide, including enteric septicemia in channel catfish and tilapia. Collectively, these species are increasingly being recognized as important pathogens in clinical and veterinary medicine. This article highlights and provides a current perspective on the taxonomy, microbiology, epidemiology, and pathogenicity of this increasingly important group.

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An Autopsy Case of <b><i>Edwardsiella tarda</i></b> Meningoencephalitis

Cited by 2 publications

References 8 publications

Acute cholecystitis with sepsis due to Edwardsiella tarda: a case report

Acute cholecystitis with sepsis due to Edwardsiella tarda: a case report

Expanding the Spectrum of Diseases and Disease Associations Caused by Edwardsiella tarda and Related Species

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