An Autologous Cell Hyaluronic Acid Graft Technique for Gingival Augmentation: A Case Series

Prato, Giovan Paolo Pini; Rotundo, Roberto; Magnani, Cristina; Soranzo, Carlo; Muzzi, Leonardo Augusto Lopes; Cairo, Francesco

doi:10.1902/jop.2003.74.2.262

Cited by 55 publications

(58 citation statements)

References 12 publications

(10 reference statements)

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“…Hyaluronic acid is a connective tissue glycosaminoglycan that enhances would healing, cell migration, and differentiation during tissue repair [26], [27]. It has been utilized for the reinforcement of periodontal ligament sheets to compensate for their fragile property and has been shown to be effective in accelerating the wound healing process [28].…”

Section: Discussionmentioning

confidence: 99%

The Effect of Brain-Derived Neurotrophic Factor on Periodontal Furcation Defects

et al. 2014

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This study aimed to observe the regenerative effect of brain-derived neurotrophic factor (BDNF) in a non-human primate furcation defect model. Class II furcation defects were created in the first and second molars of 8 non-human primates to simulate a clinical situation. The defect was filled with either, Group A: BDNF (500 µg/ml) in high-molecular weight-hyaluronic acid (HMW-HA), Group B: BDNF (50 µg/ml) in HMW-HA, Group C: HMW-HA acid only, Group D: empty defect, or Group E: BDNF (500 µg/ml) in saline. The healing status for all groups was observed at different time-points with micro computed tomography. The animals were euthanized after 11 weeks, and the tooth-bone specimens were subjected to histologic processing. The results showed that all groups seemed to successfully regenerate the alveolar buccal bone, however, only Group A regenerated the entire periodontal tissue, i.e., alveolar bone, cementum and periodontal ligament. It is suggested that the use of BDNF in combination with a scaffold such as the hyaluronic acid in periodontal furcation defects may be an effective treatment option.

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Section: Discussionmentioning

confidence: 99%

The Effect of Brain-Derived Neurotrophic Factor on Periodontal Furcation Defects

et al. 2014

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“…Prato et al . [20] studied gingival augmentation with an autologous cell HA and reported significant results with the complete coverage. Pendyala et al .…”

Section: Discussionmentioning

confidence: 99%

Hyaluronic acid: Hope of light to black triangles

Tanwar

Hungund

2016

J Int Soc Prevent Communit Dent

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Interdental papilla construction, especially in the esthetic area, is one of the most challenging tasks. Interdental papilla loss might occur due to several reasons as a consequence of periodontal surgery or trauma. The purpose of this study is to report the reconstruction of lost interdental papilla using hyaluronic acid gel. Hyaluronic acid is a glycosaminoglycan molecule with anti-inflammatory, anti-edematous properties on periodontal tissues invaded by submicrobial flora. It enhances wound healing and accelerates periodontal repair and regeneration. In addition to the field of dentistry, it has been used in other fields such as orthopedics, ophthalmology, and dermatology. It shows growth factor interaction, regulates osmotic pressure, and enhances tissue lubrication, which helps in maintaining the structural and homeostatic integrity of tissues, hence resulting in beneficial effect on lost interdental papilla. This study was aimed to reconstruct the lost interdental papilla by injecting 0.2% hyaluronic acid via nonsurgical approach. It is a noninvasive approach which reduces patient's postoperative discomfort with marked variations in the volume of interdental papilla before and after the procedure. As sufficient information is not available regarding the effectiveness of hyaluronic acid in interdental papilla construction, this study was conducted.

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“…Los estudios con fibroblastos humanos pretenden aumentar cantidad de encía queratinizada (58,59,60,62) . Está claro que es posible generar encía queratinizada con estos materiales, pero no en gran cantidad (60) .…”

Section: Discussionunclassified

“…En el 2000, Pini Prato y col. (58,59) reportó varios casos de aumento de encía con implantación de fibroblastos autólogos. El cultivo lo hacía sobre una membrana tridimensional de hidroxiapatita cuya matriz era ester benzil de ácido hialurónico.…”

Section: Sustitutos Derivados De Fibroblastos Humanosunclassified

Aplicación de biomateriales de base biológica, moléculas bioactivas e ingeniería de tejidos en cirugía plástica periodontal: Una revisión

Yaneth

Alarcón

Velásquez³

2012

Rev. Clin. Periodoncia Implantol. Rehabil. Oral

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An Autologous Cell Hyaluronic Acid Graft Technique for Gingival Augmentation: A Case Series

Cited by 55 publications

References 12 publications

The Effect of Brain-Derived Neurotrophic Factor on Periodontal Furcation Defects

The Effect of Brain-Derived Neurotrophic Factor on Periodontal Furcation Defects

Hyaluronic acid: Hope of light to black triangles

Aplicación de biomateriales de base biológica, moléculas bioactivas e ingeniería de tejidos en cirugía plástica periodontal: Una revisión

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