An auto-controlled prospective comparison of two embryos culture media (G III series versus ISM) for IVF and ICSI treatments

Abstract

Purpose To compare the effects of 2 different media on embryo morphology and development at days 2/3. Method Six hundred seventy-six attempts from 512 couples were included in this prospective auto-controlled study. Sibling oocytes of all couples undergoing an IVF (n=286) or ICSI (n=390) attempt were randomly assigned to either GIII series (Vitrolife) or ISM (Medicult) media. Primary end points were fertilization and embryo morphology rates. Conclusions Embryo morphology at days 2/3 was significantly enhanced when the embryos were cultured in GIII series.

Perceived Stress and its Social-Individual Predicors among Infertile Couples Referring to Infertility Center of Alzahra Hospital in Tabriz in 2013

“…In the results of this study, the etiology of infertility was one of the other predictors of perceived stress among men such that in men whose were expressed as the etiology of infertility, had higher perceived stress, the simultaneous availability of men and women etiologies was in lower rank due to perceived stress grade. The study by Sifer et al on the couples who were referred for IVF treatment, described the infertility stress higher in women compared to men while in men's infertility problem, stress is higher in women and men compared to when the etiology is women's problem and such findings is consistent with our study (30) which probably the reason of higher stress in infertility due to men's reasons is the available cultural issues in the society and men's infertility is assumed as an strange and far-fetched factor and for most of the people, the occurrence of such problem is not acceptable in men. In the current study, the occupational status of men was one of the other predictors of perceived stress such that the lowest grade of perceived stress was obtained among employees and the highest grade was obtained among workers which is assumed that economically workers are under pressure in supplying the higher expenses of infertility treatment compared to employees who have a fixed income for treatment expenses so the workers tolerate higher stress.…”

New candidate genes to predict pregnancy outcome in single embryo transfer cycles when using cumulus cell gene expression

“…TRPM7 is proposed to be an important predictor for topmorphology embryos on day 3 of culture in both studies. It should be noted that different culture media used in the two studies may result in different embryo development (26). This can in part explain the fact that we did not find exactly the same morphology models in the present dataset as in our previous study.…”

Optimal Human Embryo Culture

“…The inability to identity a single optimum media is reflected by examining the numerous studies in the literature comparing one medium against another. 22 Indeed, when examining prospective trials using sibling oocytes splits or patient randomization, comparison of different sequential media [23][24][25][26][27][28][29] and comparisons between single-step culture media and sequential media [30][31][32][33][34] fail to identify a superior approach or product (►Tables 2-5). These studies are often underpowered and not rigorously controlled, thus making it difficult to draw definitive conclusions.…”