An audit of using the H Pipelle for endometrial sampling at outpatient hysteroscopy and literature review comparison with the Pipelle de Cornier

Daccò, Maria Diletta; Moustafa, Mohamed; Papoutsis, Dimitrios; Georgantzis, Dimitrios; Halmos, Gábor; Magos, Adam

doi:10.1016/j.ejogrb.2012.07.021

Cited by 6 publications

(8 citation statements)

References 24 publications

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“…The Pipelle H optimizes endometrium sampling during the procedure of diagnostic hysteroscopy (37,38). The Pipelle H is twice longer (50 cm), but has the same external and internal diameters as the genuine Pipelle de Cornier (29). The device enables appropriate suction to collect a sufficient volume of endometrial tissue.…”

Section: Pipelle Sampling Device and Its Modificationsmentioning

confidence: 99%

“…Since the beginning of the ’80s, hysteroscopies have been a way to provide clinicians with direct visualization of the cervical canal and the uterine cavity ( 28 ). Hysteroscopy is acknowledged to be very useful and informative procedure of uterine cavity assessment for endometrial and intrauterine abnormalities associated with both pre- and postmenopausal abnormal uterine bleeding ( 29 , 30 ). Nowadays, the investigation is usually done in an outpatient setting.…”

Section: Overview On Diagnostic Modalities For Detection Of Endometrial Carcinomamentioning

confidence: 99%

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Current role of Pipelle endometrial sampling in early diagnosis of endometrial cancer

Terzić¹,

Aimagambetova²,

Terzić³

et al. 2020

Transl Cancer Res TCR

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Endometrial cancer is the most common gynecologic cancer in developed countries. The most prevalent, however not pathognomonic symptom of the disease is abnormal uterine bleeding. The diagnosis of endometrial cancer is based on the histologic results of endometrial sampling. Endometrial biopsy could be obtained using different modalities: hysteroscopy-directed endometrial biopsy, uterine curettage or office endometrial biopsy. Outpatient endometrial biopsy using different devices for the evaluation of abnormal uterine bleeding is gaining popularity. The most popular office-based device for endometrial sampling procedure is the Pipelle device. Currently, Pipelle endometrial sampling is widely used to diagnose endometrial cancer in women with abnormal uterine bleeding and/or postmenopausal bleeding. The method became very useful due to easiness and simplicity of the procedure, availability of a device, as well as high sensitivity in detecting endometrial cancer. Many studies compared the validity and accuracy of Pipelle biopsy with dilation and curettage in the detection of various endometrial pathologies. Published results state that Pipelle biopsy and uterine curettage are almost equally reliable in the evaluation of endometrial pathologies. Moreover, Pipelle biopsy appears more beneficial as it does not require hospital admission and anaesthesia. However, it is proven the Pipelle technique has a limited capacity to identify endometrial polyps, and some authors, based on their study, claim that dilation and curettage is a more reliable method in terms of correlation with the final histological results. In addition, there are many factors affecting the efficiency of the endometrial biopsy. Failure to get samples that are adequate for histological examination is one of the problems associated with Pipelle sampling. The above mentioned contradictory conclusions by different researchers and lack of guidance to avoid inadequate sampling present the demand for further studies on the comparison of Pipelle biopsy and uterine curettage efficiency and accuracy.

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Section: Pipelle Sampling Device and Its Modificationsmentioning

confidence: 99%

Section: Overview On Diagnostic Modalities For Detection Of Endometrial Carcinomamentioning

confidence: 99%

Current role of Pipelle endometrial sampling in early diagnosis of endometrial cancer

Terzić¹,

Aimagambetova²,

Terzić³

et al. 2020

Transl Cancer Res TCR

View full text Add to dashboard Cite

show abstract

“…2. "Pipelle Н" has the same outer and inner diameters as "Pipelle de cornier" and is 50 cm long [12]. "Pipelle H" device was developed at the Royal Free Hospital in London for histological sampling during routine hysteroscopies.…”

Section: The Main Findings and Resultsmentioning

confidence: 99%

Modern Methods of Early Detection of Endometrial Cancer on the Example of “Pipelle” Urogenital Probe

Atakhanova¹,

Abdinazarova

Tursunova³

2021

IJPBMS

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Today, at a time when cancer is developing rapidly, a number of scientific studies are being conducted worldwide in the field of early detection, prevention and treatment of the disease. A number of new methods are being recommended by experts to put into practice, which is convenient, effective, rapid, uncomplicated and painless methods of early detection of tumor diseases especially uterine cancer in women.

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“…Endometrial tissue samples were obtained by pipelle sampling with inner membrane in the secretory phase including two endometrial gland cells and stromal cells. 15 …”

Section: Methodsmentioning

confidence: 99%

Exploring the Potential Key IncRNAs with Endometriosis by Construction of a ceRNA Network

Gu¹,

Meng²,

Meng³

et al. 2021

IJGM

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The etiology and pathophysiology of endometriosis remain unclear. Current research indicates long noncoding RNA (lncRNA) may play an important role in the pathogenesis and development of endometriosis. However, the molecular mechanism of lncRNA in endometriosis is far from clear. Patients and Methods: The lncRNA and mRNA expression of 8 patients with ovarian endometriosis were determined by high-throughput RNA sequencing (8 ectopic endometria samples vs 8 eutopic endometria samples), and miRNA expression profiles were obtained from our previous study. Then a lncRNA-associated competing endogenous RNA (ceRNA) network was constructed by combining the regulatory interaction and negative co-expression interaction between the differentially expressed lncRNAs/mRNAs and miRNAs by different rules. Results: The constructed lncRNA-related ceRNA network was composed of two separate networks, network 1 including 14,137 dysregulated lncRNA-mRNA interactions, referring to 242 lncRNAs, 55 miRNAs and 1600 mRNAs, network 2 including 4459 dysregulated lncRNA-mRNA interactions, referring to 111 lncRNAs, 39 miRNAs and 1151 mRNAs. The top six hub lncRNAs (LINC01140, MSC-AS1, HAGLR, CKMT2-AS1, JAKMIP2-AS1, AL365361.1) in the significant ternary relationship of mRNA-miRNA-lncRNA in network 1, and the top six hub lncRNAs (PAX8-AS1, MIR17HC, PART1, HOXA-AS3, PLAC4, LINC00511) in the significant ternary relationship of mRNA-miRNA-lncRNA in network 2 were selected. Functional enrichment analysis of these lncRNA-related mRNAs indicated that the lncRNAs in network 1 mainly take part in positive regulation of phagocytosis, myeloid leukocyte activation, and tissue remodeling, while the lncRNAs in network 2 mainly take part in negative regulation of cell proliferation, blood vessel development and regulation of epithelial cell differentiation, which is consistent with the results obtained from the different rules to construct the networks. Conclusion: lncRNA-related ceRNA network analysis recognized key lncRNAs related to the development of endometriosis.

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An audit of using the H Pipelle for endometrial sampling at outpatient hysteroscopy and literature review comparison with the Pipelle de Cornier

Cited by 6 publications

References 24 publications

Current role of Pipelle endometrial sampling in early diagnosis of endometrial cancer

Current role of Pipelle endometrial sampling in early diagnosis of endometrial cancer

Modern Methods of Early Detection of Endometrial Cancer on the Example of “Pipelle” Urogenital Probe

Exploring the Potential Key IncRNAs with Endometriosis by Construction of a ceRNA Network

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