An Atypical Presentation of Pancreatic Pseudocyst Masquerading as Solid Pseudopapillary Neoplasm of Pancreas

Abstract

Pancreatic pseudocysts are the most common cystic lesions of the pancreas, and often present as a consequence of acute or chronic pancreatitis. On the other hand, cystic neoplasms of the pancreas are rare, but pose a significant diagnostic challenge. The differentiation between these entities often relies on the clinical features and characteristic radiological evidence. However, the diagnostic dilemma persists, leading to misdiagnosis and inappropriate treatment. We present a case of pancreatic pseudocyst in a 49-year-old male, which clinically and radiologically mimicked solid pseudopapillary neoplasm, a rare type of cystic neoplasm of the pancreas.

Solid Pseudopapillary Neoplasm of the Pancreas: Unfolding an Intriguing Condition

“…Main differential diagnosis of SPN include low-grade pancreatic neuroendocrine tumors (pNETs) in adults and pancreatoblastoma (PB) in children [10,38,39]. Pseudocyst and other pancreatic cystic neoplasms such as serous cystadenoma (SCA) and mucinous cystic neoplasm (MCN) should also be considered [9,10,39,40]. pNET pNET is the major entity when considering differential diagnosis of SPNs in the adult.…”